Allogeneic bone marrow transplantation in hematologic disorders of childhood: New trends and controversies

E. Barth, C. Malorgio, P. Tamaro

Research output: Contribution to journalArticle

Abstract

Bone marrow transplantation (BMT) represents an important therapeutic choice for several kinds of disorders: hematologic, metabolic and neoplastic pathologies can be treated with this strategy. The aim of this article is to describe the main indications for allogeneic BMT in haematologic disorders of childhood and possible problems related to this procedure. We consider only hematologic aspects, paying particular attention to unusual disorders of infancy as myelodysplastic syndromes and aplastic anemia. We also consider quality of life after a BMT in patients with sickle cell anemia and thalassemia major and compare this with quality of life of patients receiving chronic periodic blood transfusions. (C) 2000, Ferrata Storti Foundation.

Original languageEnglish
Pages (from-to)2-8
Number of pages7
JournalHaematologica
Volume85
Issue number11 SUPPL.
Publication statusPublished - 2000

Keywords

  • ALL
  • Allogeneic bone marrow transplantation
  • AML
  • Childhood
  • CML
  • Hematologic disorders
  • HR-ALL
  • Infancy
  • Myelodysplastic syndromes
  • Pediatric
  • Severe aplastic anemia
  • Sickle cell anemia
  • Thalassemia major

ASJC Scopus subject areas

  • Hematology

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