Alopecia areata is an immunologic disease associated with autoimmune conditions eg vitiligo and thyroid diseases. Down's syndrome may frequently be associated with autoimmune disorders. Alopecia areata has been reported to occur more often in Down's syndrome than in the general population. According to the literature alopecia areata in Down's syndrome usually shows a poor prognosis. Since 1985 we have followed 21 patients with Down's syndrome among 1560 cases of alopecia areata. During the follow-up period, only 2 out of the 21 patients showed an improvement of their alopecia areata. 7 patients had spreading of their disease and 12 had persistence of their condition despite of the topical immunotherapy with SADBE.
|Number of pages||4|
|Journal||Giornale Italiano di Dermatologia e Venereologia|
|Publication status||Published - 1994|
ASJC Scopus subject areas