TY - JOUR
T1 - Alpha-2-macroglobulin gene, oxidized low-density lipoprotein receptor-1 locus, and sporadic Alzheimer's disease
AU - Colacicco, Anna Maria
AU - Solfrizzi, Vincenzo
AU - D'Introno, Alessia
AU - Capurso, Cristiano
AU - Kehoe, Patrick G.
AU - Seripa, Davide
AU - Pilotto, Alberto
AU - Santamato, Andrea
AU - Capurso, Antonio
AU - Panza, Francesco
PY - 2009/9
Y1 - 2009/9
N2 - A total sample of 169 AD patients, and 264 age- and sex-matched unrelated caregivers from Apulia, southern Italy, were genotypized for alpha-2-macroglobulin (A2M) Val1000/Ile single-nucleotide polymorphism (SNP) (rs669), apolipoprotein E (APOE), and SNPs (+1073 and +1071) in the oxidized low-density lipoprotein receptor-1 (OLR1) gene on chromosome 12. A2M allele and genotype frequencies were similar between AD patients and controls, also after stratification for late onset (≥70 years) and early onset (
AB - A total sample of 169 AD patients, and 264 age- and sex-matched unrelated caregivers from Apulia, southern Italy, were genotypized for alpha-2-macroglobulin (A2M) Val1000/Ile single-nucleotide polymorphism (SNP) (rs669), apolipoprotein E (APOE), and SNPs (+1073 and +1071) in the oxidized low-density lipoprotein receptor-1 (OLR1) gene on chromosome 12. A2M allele and genotype frequencies were similar between AD patients and controls, also after stratification for late onset (≥70 years) and early onset (
KW - Alpha-2-macroglobulin (A2M)
KW - Alzheimer's disease
KW - Apolipoprotein E
KW - Chromosome 12
KW - Dementia
KW - Oxidized low-density lipoprotein receptor-1 (OLR1)
UR - http://www.scopus.com/inward/record.url?scp=67650495870&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67650495870&partnerID=8YFLogxK
U2 - 10.1016/j.neurobiolaging.2007.11.015
DO - 10.1016/j.neurobiolaging.2007.11.015
M3 - Article
C2 - 18191876
AN - SCOPUS:67650495870
VL - 30
SP - 1518
EP - 1520
JO - Neurobiology of Aging
JF - Neurobiology of Aging
SN - 0197-4580
IS - 9
ER -