Alpha, beta and gamma Human Papillomaviruses in the anal canal of HIV-infected and uninfected men who have sex with men

Maria Gabriella Donà; Tarik Gheit; Alessandra Latini; Maria Benevolo; Montserrat Torres; Vitaly Smelov; Sandrine McKay-Chopin; Amalia Giglio; Antonio Cristaudo; Mauro Zaccarelli; Massimo Tommasino; Massimo Giuliani

doi:10.1016/j.jinf.2015.02.001

Alpha, beta and gamma Human Papillomaviruses in the anal canal of HIV-infected and uninfected men who have sex with men

Maria Gabriella Donà, Tarik Gheit, Alessandra Latini, Maria Benevolo, Montserrat Torres, Vitaly Smelov, Sandrine McKay-Chopin, Amalia Giglio, Antonio Cristaudo, Mauro Zaccarelli, Massimo Tommasino, Massimo Giuliani

Research output: Contribution to journal › Article

Abstract

Objectives: Anal infection by cutaneous Human Papillomaviruses (HPV) has been rarely investigated. We aimed to assess the prevalence, genotype diversity, and determinants of mucosal (alpha) and cutaneous (beta and gamma) anal HPV infection in men who have sex with men (MSM). Methods: Anal samples were collected with a Dacron swab. Alpha HPVs were detected using the Linear Array HPV genotyping test, while beta and gamma HPVs using a PCR combined with Luminex technology. Results: A total of 609 MSM (437 HIV-uninfected and 172 HIV-infected, most of which were undergoing cART) were enrolled. Alpha, beta, and gamma HPVs were detected in 78.0%, 27.6% and 29.3% of the participants. Only alpha HPV prevalence was significantly higher among HIV-infected compared to uninfected MSM (93.0% vs. 72.1%, p

Original language	English
Pages (from-to)	74-84
Number of pages	11
Journal	Journal of Infection
Volume	71
Issue number	1
DOIs	https://doi.org/10.1016/j.jinf.2015.02.001
Publication status	Published - Jul 1 2015

Keywords

Anal canal
Cutaneous
HIV
Human Papillomavirus
Infection
Men who have sex with men
Mucosal

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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Donà, M. G., Gheit, T., Latini, A., Benevolo, M., Torres, M., Smelov, V., McKay-Chopin, S., Giglio, A., Cristaudo, A., Zaccarelli, M., Tommasino, M., & Giuliani, M. (2015). Alpha, beta and gamma Human Papillomaviruses in the anal canal of HIV-infected and uninfected men who have sex with men. Journal of Infection, 71(1), 74-84. https://doi.org/10.1016/j.jinf.2015.02.001

Alpha, beta and gamma Human Papillomaviruses in the anal canal of HIV-infected and uninfected men who have sex with men. / Donà, Maria Gabriella; Gheit, Tarik; Latini, Alessandra ; Benevolo, Maria; Torres, Montserrat; Smelov, Vitaly; McKay-Chopin, Sandrine; Giglio, Amalia ; Cristaudo, Antonio ; Zaccarelli, Mauro; Tommasino, Massimo; Giuliani, Massimo.

In: Journal of Infection, Vol. 71, No. 1, 01.07.2015, p. 74-84.

Research output: Contribution to journal › Article

Donà, MG, Gheit, T, Latini, A , Benevolo, M, Torres, M, Smelov, V, McKay-Chopin, S, Giglio, A , Cristaudo, A , Zaccarelli, M, Tommasino, M & Giuliani, M 2015, 'Alpha, beta and gamma Human Papillomaviruses in the anal canal of HIV-infected and uninfected men who have sex with men', Journal of Infection, vol. 71, no. 1, pp. 74-84. https://doi.org/10.1016/j.jinf.2015.02.001

Donà, Maria Gabriella ; Gheit, Tarik ; Latini, Alessandra ; Benevolo, Maria ; Torres, Montserrat ; Smelov, Vitaly ; McKay-Chopin, Sandrine ; Giglio, Amalia ; Cristaudo, Antonio ; Zaccarelli, Mauro ; Tommasino, Massimo ; Giuliani, Massimo. / Alpha, beta and gamma Human Papillomaviruses in the anal canal of HIV-infected and uninfected men who have sex with men. In: Journal of Infection. 2015 ; Vol. 71, No. 1. pp. 74-84.

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AU - Torres, Montserrat

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AU - McKay-Chopin, Sandrine

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