Alterations of cardiac structure in patients with isolated office, ambulatory, or home hypertension: Data from the general population (Pressione Arteriose Monitorate E Loro Associazioni [PAMELA] Study)

Roberto Sega, Giuseppe Trocino, Arturo Lanzarotti, Stefano Carugo, Giancarlo Cesana, Riccardo Schiavina, Franco Valagussa, Michele Bombelli, Cristina Giannattasio, Alberto Zanchetti, Giuseppe Mancia

Research output: Contribution to journalArticle

Abstract

Background - The prevalence and clinical significance of isolated office (or white coat) hypertension is controversial, and population data are limited. We studied the prevalence of this condition and its association with echocardiographic left ventricular mass in the general population of the PAMELA (Pressione Arteriose Monitorate E Loro Associazioni) Study. Methods and Results - The study involved a large, randomized sample (n=3200) representative of the Monza (Milan) population, 25 to 74 years of age. Participants in the study (64% of the sample) underwent measurements of office, home, 24-hour ambulatory blood pressure, and echocardiography. Isolated office hypertension was defined as systolic or diastolic values ≥140 mm Hg or ≥90 mm Hg respectively. Home and ambulatory normotension were defined according to criteria previously established from the PAMELA Study, for example,

Original languageEnglish
Pages (from-to)1385-1392
Number of pages8
JournalCirculation
Volume104
Issue number12
Publication statusPublished - Sep 18 2001

Keywords

  • Blood pressure
  • Hypertension
  • Hypertrophy

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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    Sega, R., Trocino, G., Lanzarotti, A., Carugo, S., Cesana, G., Schiavina, R., Valagussa, F., Bombelli, M., Giannattasio, C., Zanchetti, A., & Mancia, G. (2001). Alterations of cardiac structure in patients with isolated office, ambulatory, or home hypertension: Data from the general population (Pressione Arteriose Monitorate E Loro Associazioni [PAMELA] Study). Circulation, 104(12), 1385-1392.