Altered subthalamo-pallidal synchronisation in parkinsonian dyskinesias

G. Foffani, G. Ardolino, B. Meda, M. Egidi, P. Rampini, E. Caputo, G. Baselli, Alberto Priori

Research output: Contribution to journalArticle

Abstract

The aim of this work was to study the role of subthalamo-pallidal synchronisation in the pathophysiology of dyskinesias. We recorded local field potentials (LFPs) in a patient with Parkinson's disease and left surgery induced dyskinesias with double, bilateral deep brain stimulation electrode implants in the subthalamic nucleus (STN) and the globus pallidus internus [GPi). Synchronisation was studied through coherence analysis. In the nuclei contralateral to the dyskinetic side of the body there was decreased STN-GPi coherence in the high beta range (20-30 Hz) and an enhanced coherence at low frequencies (

Original languageEnglish
Pages (from-to)426-428
Number of pages3
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume76
Issue number3
DOIs
Publication statusPublished - Mar 2005

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

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