Abstract
We have studied the effect of Ambroxol on the production of Interleukin-1 (IL-1) and Tumor Necrosis Factor (TNF) in human mononuclear cells (MNC). For this purpose MNC were cultured for 24 h in the presence of endotoxin and different doses of Ambroxol. The results indicate that Ambroxol markedly inhibited IL-1 and TNF production at doses of 10-100 μg/ml, without any apparent toxicity.
Original language | English |
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Pages (from-to) | 275-279 |
Number of pages | 5 |
Journal | Agents and Actions |
Volume | 31 |
Issue number | 3-4 |
DOIs | |
Publication status | Published - Nov 1990 |
ASJC Scopus subject areas
- Toxicology
- Pharmacology (medical)