Ambulatory blood pressure, blood pressure variability and antihypertensive treatment

G. Mancia, S. Omboni

Research output: Contribution to journalArticlepeer-review


Ambulatory blood pressure monitoring is frequently employed in the clinical practice to improve the diagnosis of hypertension and the appropriateness of the decision regarding initiation of antihypertensive treatment. It is also frequently employed to check the efficacy of this treatment in conditions resembling daily life. This paper will describe the effect of a number of antihypertensive drugs on ambulatory blood pressure, based on data collected by our group in the past 10 years. It will then discuss the advantages of ambulatory blood pressure in studies on efficacy of antihypertensive drugs and the importance of this approach for definition of the trough-to-peak ratio of the antihypertensive effect. Some technical and clinical problems inherent to the ambulatory blood pressure monitoring approach will also be discussed.

Original languageEnglish
Pages (from-to)449-462
Number of pages14
JournalClinical and Experimental Hypertension
Issue number3-4
Publication statusPublished - 1996


  • ACE-inhibitors
  • ambulatory blood pressure monitoring
  • antihypertensive treatment
  • blood pressure variability
  • calcium-antagonists
  • clinic blood pressure

ASJC Scopus subject areas

  • Internal Medicine


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