Ambulatory blood pressure in normotensive and hypertensive subjects: Results from an international database

Jan A. Staessen, Eoin T. O’Brien, Antoon K. Amery, Neil Atkins, Peter Baumgart, Paul De Cort, Jean Paul Degaute, Primoz Dolenc, Regis De Gaudemaris, Inger Enström, Robert Fagard, Philippe Gosse, Steve Gourlay, Hiroshi Hayashi, Yutaka Imai, Gary James, Terukazu Kawasaki, Emilio Kuschnir, Iwao Kuwajima, Lars LindholmLisheng Liu, Franco Macor, Giuseppe Mancia, Barry McGrath, Martin Middeke, Jian Ming, Stefano Omboni, Kuniaka Otsuka, Paolo Palatini, Gianfranco Parati, Carl Pieper, Paolo Verdecchia, Prince Zachariah, Weizhong Zhang

Research output: Contribution to journalArticlepeer-review


Objective: To delineate more precisely an operational threshold for making clinical decisions based on ambulatory blood pressure (ABP) measurement by studying the ABP in subjects who were diagnosed as either normotensive or hypertensive by conventional blood pressure (CBP) measurement. Subjects: Twenty-four research groups recruited 7069 subjects. Of these, 4577 were normotensive (CBP 160 mmHg) and 1310 had diastolic hypertension (diastolic CBP >95 mmHg). Combined systolic and diastolic hypertension was present in 861 subjects. Hypertension had been diagnosed from the mean of two to nine (median two) CBP measurements obtained at one to three (median two) visits. Results: The 95th centiles of the ABP distributions in the normotensive subjects were (systolic and diastolic, respectively) 133 and 82 mmHg for 24-h ABP, 140 and 88 mmHg for daytime ABP and 125 and 76 mmHg for night-time ABP, respectively. Of the subjects with systolic hypertension, 24% had 24-h systolic ABP

Original languageEnglish
Pages (from-to)S13-S22
JournalJournal of Hypertension
Publication statusPublished - 1994


  • Ambulatory blood pressure
  • Blood pressure measurement
  • Conventional blood pressure
  • Hypertension
  • Normotension

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Internal Medicine


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