Abstract
Ambulatory monitoring (VEST) of left ventricular (LV) function is a useful and accurate method to measure cardiac function during exercise and rest. The aim of this study was to evaluate LV response to exercise in normal sedentary subjects. Methods: Ten normal sedentary subjects underwent continuous ambulatory monitoring of LV function by VEST during upright bicycle exercise associated with combined analysis of pulmonary gas exchange. All parameters of LV function were measured in control conditions at rest, at the anaerobic threshold (point of nonlinear increase in ventilation relative to oxygen uptake) and at peak oxygen uptake (peak VO2). Results: Heart rate and cardiac output significantly increased from control conditions to anaerobic threshold (p <0.001) and from anaerobic threshold to peak VO2 (p <0.001). Ejection fraction, end diastolic volume and stroke volume significantly increased from control conditions to anaerobic threshold (p <0.001), showing no significant change from anaerobic threshold to peak VO2. Finally, end- systolic volume significantly decreased from control conditions to anaerobic threshold (p <0.001), showing no significant change from anaerobic threshold to peak VO2. Conclusion: VEST is particularly useful in the evaluation of cardiac response to exercise in normal sedentary subjects, providing a better understanding of the spectrum of the normal LVEF response to exercise. Our data demonstrate that ejection fraction response to exercise is variable after anaerobic threshold, and a uniform increase is not necessarily expected in normal sedentary subjects.
| Original language | English |
|---|---|
| Pages (from-to) | 564-568 |
| Number of pages | 5 |
| Journal | Journal of Nuclear Medicine |
| Volume | 36 |
| Issue number | 4 |
| Publication status | Published - 1995 |
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Keywords
- anaerobic threshold
- cardiopulmonary exercise test
- left ventricular function
- vest
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
Cite this
Ambulatory monitoring of left ventricular function during cardiopulmonary exercise tests in normal sedentary subjects. / Imbriaco, M.; Cuocolo, A.; Pace, L.; Nappi, A.; Nicolai, E.; Cardei, S.; Morisco, C.; Romano, M.; Salvatore, M.
In: Journal of Nuclear Medicine, Vol. 36, No. 4, 1995, p. 564-568.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ambulatory monitoring of left ventricular function during cardiopulmonary exercise tests in normal sedentary subjects
AU - Imbriaco, M.
AU - Cuocolo, A.
AU - Pace, L.
AU - Nappi, A.
AU - Nicolai, E.
AU - Cardei, S.
AU - Morisco, C.
AU - Romano, M.
AU - Salvatore, M.
PY - 1995
Y1 - 1995
N2 - Ambulatory monitoring (VEST) of left ventricular (LV) function is a useful and accurate method to measure cardiac function during exercise and rest. The aim of this study was to evaluate LV response to exercise in normal sedentary subjects. Methods: Ten normal sedentary subjects underwent continuous ambulatory monitoring of LV function by VEST during upright bicycle exercise associated with combined analysis of pulmonary gas exchange. All parameters of LV function were measured in control conditions at rest, at the anaerobic threshold (point of nonlinear increase in ventilation relative to oxygen uptake) and at peak oxygen uptake (peak VO2). Results: Heart rate and cardiac output significantly increased from control conditions to anaerobic threshold (p <0.001) and from anaerobic threshold to peak VO2 (p <0.001). Ejection fraction, end diastolic volume and stroke volume significantly increased from control conditions to anaerobic threshold (p <0.001), showing no significant change from anaerobic threshold to peak VO2. Finally, end- systolic volume significantly decreased from control conditions to anaerobic threshold (p <0.001), showing no significant change from anaerobic threshold to peak VO2. Conclusion: VEST is particularly useful in the evaluation of cardiac response to exercise in normal sedentary subjects, providing a better understanding of the spectrum of the normal LVEF response to exercise. Our data demonstrate that ejection fraction response to exercise is variable after anaerobic threshold, and a uniform increase is not necessarily expected in normal sedentary subjects.
AB - Ambulatory monitoring (VEST) of left ventricular (LV) function is a useful and accurate method to measure cardiac function during exercise and rest. The aim of this study was to evaluate LV response to exercise in normal sedentary subjects. Methods: Ten normal sedentary subjects underwent continuous ambulatory monitoring of LV function by VEST during upright bicycle exercise associated with combined analysis of pulmonary gas exchange. All parameters of LV function were measured in control conditions at rest, at the anaerobic threshold (point of nonlinear increase in ventilation relative to oxygen uptake) and at peak oxygen uptake (peak VO2). Results: Heart rate and cardiac output significantly increased from control conditions to anaerobic threshold (p <0.001) and from anaerobic threshold to peak VO2 (p <0.001). Ejection fraction, end diastolic volume and stroke volume significantly increased from control conditions to anaerobic threshold (p <0.001), showing no significant change from anaerobic threshold to peak VO2. Finally, end- systolic volume significantly decreased from control conditions to anaerobic threshold (p <0.001), showing no significant change from anaerobic threshold to peak VO2. Conclusion: VEST is particularly useful in the evaluation of cardiac response to exercise in normal sedentary subjects, providing a better understanding of the spectrum of the normal LVEF response to exercise. Our data demonstrate that ejection fraction response to exercise is variable after anaerobic threshold, and a uniform increase is not necessarily expected in normal sedentary subjects.
KW - anaerobic threshold
KW - cardiopulmonary exercise test
KW - left ventricular function
KW - vest
UR - http://www.scopus.com/inward/record.url?scp=0028964786&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028964786&partnerID=8YFLogxK
M3 - Article
VL - 36
SP - 564
EP - 568
JO - Journal of Nuclear Medicine
JF - Journal of Nuclear Medicine
SN - 0161-5505
IS - 4
ER -