Ambulatory polysomnography of never-depressed borderline subjects: A high-risk approach to rapid eye movement latency

Marco Battaglia, Luigi Ferini-Strambi, Salvatore Smirne, Luana Bernardeschi, Laura Bellodi

Research output: Contribution to journalArticle


The sleep parameters of never-depressed borderline subjects and age- and sex-matched normal controls were compared by continuous 48-hr ambulatory electroencephalographic (EEG) monitoring. Borderline subjects had a significantly shorter rapid eye movement latency, normal architecture of rapid eye movements sleep, and had familial risks for mood disorders four times greater than in the families of controls. Reduced latency of rapid eye movement can be a trait indicator of liability to depression, present before the clinical appearance of the disorder, and demonstrable in a putative high-risk population.

Original languageEnglish
Pages (from-to)326-334
Number of pages9
JournalBiological Psychiatry
Issue number5
Publication statusPublished - Mar 1 1993



  • Ambulatory polysomnography
  • borderline personality disorder
  • REM

ASJC Scopus subject areas

  • Biological Psychiatry

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