American-European Consensus Conference on ARDS, Part 2. Ventilatory, pharmacologic, supportive therapy, study design strategies and issues related to recovery and remodeling

A. Artigas, G. R. Bernard, J. Carlet, D. Dreyfuss, L. Gattinoni, L. Hudson, M. Lamy, J. J. Marini, M. A. Matthay, M. R. Pinsky, R. Spragg, P. M. Suter

Research output: Contribution to journalArticlepeer-review

Abstract

The acute respiratory distress syndrome (ARDS) continues as a contributor to the morbidity and mortality of patients in intensive care units throughout the world, imparting tremendous human and financial costs. During the last ten years there has been a decline in ARDS mortality without a clear explanation. The American-European Consensus Committee on ARDS was formed to re-evaluate the standards for the ICU care of patients with acute lung injury (ALI), with regard to ventilatory strategies, the more promising pharmacologic agents, and the definition and quantification of pathological features of ALI that require resolution. It was felt that the definition of strategies for the clinical design and coordination of studies between centers and continents was becoming increasingly important to facilitate the study of various new therapies for ARDS.

Original languageEnglish
Pages (from-to)378-398
Number of pages21
JournalIntensive Care Medicine
Volume24
Issue number4
DOIs
Publication statusPublished - 1998

Keywords

  • Acute lung injury
  • Adult respiratory distress syndrome
  • Coordination
  • Lung remodeling
  • Mechanical ventilation
  • Pharmacologic therapy
  • Supportive care

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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