Amitriptyline is effective in chronic but not in episodic tension-type headache: Pathogenetic implications

Rosanna Cerbo, Piero Barbanti, Giovanni Fabbrini, Maria Paola Pascali, Teresa Catarci

Research output: Contribution to journalArticle

Abstract

The tricyclic antidepressant, amitriptyline, is an effective drug for the treatment of chronic tension-type headache and for other chronic pain syndromes, but it is also effective in the prophylaxis of an episodic type of headache such as migraine. However, its efficacy in episodic tension-type headache has not yet been clarified. We compared the efficacy of amitriptyline (25 mg/day) in 82 nondepressed patients with either chronic or episodic tension-type headache in an open-label study. Amitriptyline significantly reduced (P

Original languageEnglish
Pages (from-to)453-457
Number of pages5
JournalHeadache
Volume38
Issue number6
Publication statusPublished - Jun 1998

Keywords

  • Amitriptyline
  • Chronic tension-type headache
  • Episodic tension-type headache

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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