AMOP, a protein module alternatively spliced in cancer cells

Francesca D. Ciccarelli, Tobias Doerks, Peer Bork

Research output: Contribution to journalArticlepeer-review

Abstract

This article describes a new extracellular domain - AMOP, for adhesion-associated domain in MUC4 and other proteins. This domain occurs in putative cell adhesion molecules and in some splice variants of MUC4. MUC4 splice variants are overexpressed in several tumours; in particular, they are highly expressed in pancreatic carcinomas but not in normal pancreas. The presence of AMOP in cell adhesion molecules could be indicative of a role for this domain in adhesion.

Original languageEnglish
Pages (from-to)113-115
Number of pages3
JournalTrends in Biochemical Sciences
Volume27
Issue number3
DOIs
Publication statusPublished - Mar 1 2002

ASJC Scopus subject areas

  • Biochemistry

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