Amphetamine concentrations in rat brain and human urine after fenproporex administration

G. Tognoni; P. L. Morselli; S. Garattini

doi:10.1016/0014-2999(72)90227-0

Amphetamine concentrations in rat brain and human urine after fenproporex administration

G. Tognoni, P. L. Morselli, S. Garattini

Istituto di Ricerche Farmacologiche "Mario Negri"

Research output: Contribution to journal › Article › peer-review

Abstract

After administration of fenproporex (N-2-cyanoethylamphetamine · HCl), described as an anorectic drug devoid of CNS stimulant effect, to rats and humans considerable amounts of amphetamine were found in rat brain and human urine. A consistent CNS stimulant effect was also observed both in rats and humans.

Original language	English
Pages (from-to)	125-126
Number of pages	2
Journal	European Journal of Pharmacology
Volume	20
Issue number	1
DOIs	https://doi.org/10.1016/0014-2999(72)90227-0
Publication status	Published - 1972

Keywords

Amphetamine
Fenproporex
Human urine
Rat brain

ASJC Scopus subject areas

Cellular and Molecular Neuroscience
Pharmacology

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10.1016/0014-2999(72)90227-0

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title = "Amphetamine concentrations in rat brain and human urine after fenproporex administration",

abstract = "After administration of fenproporex (N-2-cyanoethylamphetamine · HCl), described as an anorectic drug devoid of CNS stimulant effect, to rats and humans considerable amounts of amphetamine were found in rat brain and human urine. A consistent CNS stimulant effect was also observed both in rats and humans.",

keywords = "Amphetamine, Fenproporex, Human urine, Rat brain",

author = "G. Tognoni and Morselli, {P. L.} and S. Garattini",

year = "1972",

doi = "10.1016/0014-2999(72)90227-0",

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T1 - Amphetamine concentrations in rat brain and human urine after fenproporex administration

AU - Tognoni, G.

AU - Morselli, P. L.

AU - Garattini, S.

PY - 1972

Y1 - 1972

N2 - After administration of fenproporex (N-2-cyanoethylamphetamine · HCl), described as an anorectic drug devoid of CNS stimulant effect, to rats and humans considerable amounts of amphetamine were found in rat brain and human urine. A consistent CNS stimulant effect was also observed both in rats and humans.

AB - After administration of fenproporex (N-2-cyanoethylamphetamine · HCl), described as an anorectic drug devoid of CNS stimulant effect, to rats and humans considerable amounts of amphetamine were found in rat brain and human urine. A consistent CNS stimulant effect was also observed both in rats and humans.

KW - Amphetamine

KW - Fenproporex

KW - Human urine

KW - Rat brain

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ER -

Amphetamine concentrations in rat brain and human urine after fenproporex administration

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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