Amplitude reduction of the epidural cervical SEPs during voluntary movement

Angelo Insola, Paolo Mazzone, Massimiliano Valeriani

Research output: Contribution to journalArticlepeer-review


Fourteen patients, suffering from chronic pain resistant to pharmacological treatment, underwent epidural electrode implant on the cervical spinal cord (CSC) for neuromodulation. After the median nerve stimulation, somatosensory evoked potentials (SEPs) were recorded from the epidural electrode contacts, from the frontal and the parietal regions contralateral to the stimulated side, from an electrode placed over the sixth cervical vertebra and from the Erb's point. SEPs were recorded at rest and during a voluntary flexion-extension movement of the stimulated wrist. The epidural electrode contacts recorded a triphasic potential (P1-N1-P2). The epidural potential amplitude was significantly decreased during voluntary movement compared with the rest, thus suggesting that the effect of movement on SEPs occurs also at CSC level.

Original languageEnglish
Pages (from-to)317-320
Number of pages4
JournalInternational Congress Series
Publication statusPublished - Mar 2005


  • Gating
  • Neuromodulation
  • Segmental potential
  • Somatosensory evoked potential

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Amplitude reduction of the epidural cervical SEPs during voluntary movement'. Together they form a unique fingerprint.

Cite this