Amplitude spectrum area to guide resuscitation-A retrospective analysis during out-of-hospital cardiopulmonary resuscitation in 609 patients with ventricular fibrillation cardiac arrest

Giuseppe Ristagno, Yongqin Li, Francesca Fumagalli, Andrea Finzi, Weilun Quan

Research output: Contribution to journalArticle

Abstract

Introduction: The capability of amplitude spectrum area (AMSA) to predict the success of defibrillation (DF) was retrospectively evaluated in a large database of out-of-hospital cardiac arrests. Methods: Electrocardiographic data, including 1260 DFs, were obtained from 609 cardiac arrest patients due to ventricular fibrillation. AMSA sensitivity, specificity, accuracy, and positive and negative predictive values (PPV, NPV) for predicting DF success were calculated, together with receiver operating characteristic (ROC) curves. Successful DF was defined as the presence of spontaneous rhythm ≥40. bpm starting within 60. s from the DF. In 303 patients with chest compression (CC) depth data collected with an accelerometer, changes in AMSA were analyzed in relationship to CC depth. Results: AMSA was significantly higher prior to a successful DF than prior to an unsuccessful DF (15.6. ±. 0.6 vs. 7.97. ±. 0.2. mV-Hz, p97%. Area under the ROC curve was 0.84. CC depth affected AMSA value. When depth was 1.75. in. (p

Original languageEnglish
Pages (from-to)1697-1703
Number of pages7
JournalResuscitation
Volume84
Issue number12
DOIs
Publication statusPublished - Dec 2013

Keywords

  • Amplitude spectrum area
  • Defibrillation
  • Outcome
  • Prediction
  • Ventricular fibrillation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Emergency
  • Emergency Medicine

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