Abstract
We report a 57-year-old man with progressive symmetric weakness and fasciculation affecting the legs. Electromyography revealed fibrillations and neurogenic motor unit potentials in the leg muscles. Biopsy of a motor branch of the obturator nerve revealed axonal degeneration, loss of myelinated nerve fibers, and amyloidosis with deposits of lambda light chains. At 6-month follow-up, the patient manifested sensory and autonomic symptoms, and lambda light chains were first detected in the serum. In this case, diagnosis of amyloidosis remained elusive until motor nerve biopsy.
| Original language | English |
|---|---|
| Pages (from-to) | 600-602 |
| Number of pages | 3 |
| Journal | Neurology |
| Volume | 51 |
| Issue number | 2 |
| Publication status | Published - Aug 1998 |
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ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Amyloid neuropathy simulating lower motor neuron disease. / Quattrini, Angelo; Nemni, R.; Sferrazza, B.; Ricevuti, G.; Dell'Antonio, G.; Lazzerini, A.; Iannaccone, S.
In: Neurology, Vol. 51, No. 2, 08.1998, p. 600-602.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Amyloid neuropathy simulating lower motor neuron disease
AU - Quattrini, Angelo
AU - Nemni, R.
AU - Sferrazza, B.
AU - Ricevuti, G.
AU - Dell'Antonio, G.
AU - Lazzerini, A.
AU - Iannaccone, S.
PY - 1998/8
Y1 - 1998/8
N2 - We report a 57-year-old man with progressive symmetric weakness and fasciculation affecting the legs. Electromyography revealed fibrillations and neurogenic motor unit potentials in the leg muscles. Biopsy of a motor branch of the obturator nerve revealed axonal degeneration, loss of myelinated nerve fibers, and amyloidosis with deposits of lambda light chains. At 6-month follow-up, the patient manifested sensory and autonomic symptoms, and lambda light chains were first detected in the serum. In this case, diagnosis of amyloidosis remained elusive until motor nerve biopsy.
AB - We report a 57-year-old man with progressive symmetric weakness and fasciculation affecting the legs. Electromyography revealed fibrillations and neurogenic motor unit potentials in the leg muscles. Biopsy of a motor branch of the obturator nerve revealed axonal degeneration, loss of myelinated nerve fibers, and amyloidosis with deposits of lambda light chains. At 6-month follow-up, the patient manifested sensory and autonomic symptoms, and lambda light chains were first detected in the serum. In this case, diagnosis of amyloidosis remained elusive until motor nerve biopsy.
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UR - http://www.scopus.com/inward/citedby.url?scp=0031723845&partnerID=8YFLogxK
M3 - Article
C2 - 9710046
AN - SCOPUS:0031723845
VL - 51
SP - 600
EP - 602
JO - Neurology
JF - Neurology
SN - 0028-3878
IS - 2
ER -