Amyloidosis: 2008 BMT Tandem Meetings (February 13-17, San Diego)

Angela Dispenzieri, Giampaolo Merlini, Raymond L. Comenzo

Research output: Contribution to journalArticle

Abstract

AL amyloidosis is a rare disease in which immunoglobulin light chains are deposited as aggregated interstitial fibrils that can compromise organ function and lead to death. The risks that patients with amyloidosis face include late diagnosis, misdiagnosis of amyloid type, untimely and ineffective therapy, and toxicities of therapy. The goals of treatment are (1) reduction or elimination of the amyloid-forming protein, usually a free immunoglobulin light chain measured by the serum-free light chain assay; (2) support of the patient pending hematologic response and improvement; and (3) stabilization of organ function. Whenever possible, patients should be treated on clinical trials.

Original languageEnglish
Pages (from-to)6-11
Number of pages6
JournalBiology of Blood and Marrow Transplantation
Volume14
Issue number1 SUPPL.
DOIs
Publication statusPublished - Jan 2008

ASJC Scopus subject areas

  • Transplantation

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