Amyloidosis presenting with Fabry disease

Amyloidosis is a chronic disease characterized by the deposition of fibrils in various tissues and its classification depends mainly on the constituents of these fibrils. We present the case of a 69-year-old lady who presenting with secondary, AA amyloidosis, and Fabry disease leading to end stage renal disease. Long-term undiagnosed Fabry disease might have triggered a chronic inflammation with the formation of auto antibodies leading to rheumatoid arthritis and consequently secondary amyloidosis. Further studies might be required to define the state of art. So far in medical literature there are few if any of such published cases.