Amyotrophic lateral sclerosis is a degenerative disease occurring after the age of 50 years or preferentially at older age, that is characterized by a simultaneous involvement of the corticospinal tract, brainstem, and spinal anterior horn, without significant involvement of the sensitivity, autonomic and cognitive functions, with possible fatal outcome in a few years. A markedly heterogeneous clinical presentation makes the diagnosis more challenging (especially in the early stages and in case of atypical presentations ) with many other clinical conditions, such as cervical spondylotic myeloradiculopathy. In this brief review we examine the distinguishing features between these two clinical conditions, very different because of the etiology, symptoms, therapy and especially prognosis.
|Translated title of the contribution||Amyotrophic lateral sclerosis: Differential diagnosis with cervical myeloradiculopathy|
|Number of pages||4|
|Journal||Acta Medica Mediterranea|
|Publication status||Published - 2011|
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