An adolescent with rhabdomyosarcoma during pregnancy

Cristina Meazza, Michela Casanova, Elena Zaffignani, Carlo Alfredo Clerici, Francesca Favini, Roberto Vasquez, Andrea Ferrari

Research output: Contribution to journalArticlepeer-review


We report the case of a 15-year-old girl with a large gluteal and perineal rhabdomyosarcoma diagnosed at 24 weeks of pregnancy, whose management posed a great clinical dilemma for us. The patient refused to consider a therapeutic abortion, so we opted for a customized treatment with mild doses of chemotherapy administered weekly to control tumor growth while minimizing fetal and perinatal complications. After the delivery of a healthy female, we adopted a more intensive chemotherapy regimen plus irradiation. Despite an initially good response, the disease unfortunately progressed and the patient died of her disease.

Original languageEnglish
Pages (from-to)431-433
Number of pages3
Issue number3
Publication statusPublished - May 2008


  • Chemotherapy
  • Pregnancy
  • Rhabdomyosarcoma

ASJC Scopus subject areas

  • Cancer Research


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