TY - JOUR
T1 - An "all-wheel drive" proposal to accelerate clinical research in common and rare neurological diseases
AU - Salvetti, Marco
AU - Battaglia, Mario A
AU - Di Filippo, Massimiliano
AU - Mancardi, Gian Luigi
AU - Mancuso, Michelangelo
AU - Patti, Francesco
AU - Sormani, Maria Pia
AU - Zaratin, Paola
PY - 2020
Y1 - 2020
N2 - The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases.
AB - The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases.
U2 - 10.1007/s10072-019-04189-4
DO - 10.1007/s10072-019-04189-4
M3 - Review article
C2 - 31858329
SP - 789
EP - 793
JO - Neurol. Sci.
JF - Neurol. Sci.
SN - 1590-1874
ER -