An analysis of factors influencing treatment options in osteosarcoma

G. Bacci, P. Picci

Research output: Contribution to journalArticle

Abstract

During the past twenty years dramatic advances have been made in the treatment of non-metastatic osteosarcoma (OS) of the extremities in terms of cure rate and quality of life for survivors. While twenty years ago, in spite of amputation, most patients with this tumour died, today about 3/4 of them are cured an amputation is avoided. These advances are due mainly to the development of effective adjuvant and neoadjuvant chemotherapeutic regimens. This review reports on the progress and controversies in the treatment of OS occurred with respect to the construct, experimental design and interpretation of the more important studies which led to these remarkable results.

Original languageEnglish
Pages (from-to)52-65
Number of pages14
JournalFORUM - Trends in Experimental and Clinical Medicine
Volume4
Issue number1
Publication statusPublished - 1994

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Osteosarcoma
Amputation
Statistical Factor Analysis
Survivors
Research Design
Extremities
Quality of Life
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

An analysis of factors influencing treatment options in osteosarcoma. / Bacci, G.; Picci, P.

In: FORUM - Trends in Experimental and Clinical Medicine, Vol. 4, No. 1, 1994, p. 52-65.

Research output: Contribution to journalArticle

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