Abstract
During the past twenty years dramatic advances have been made in the treatment of non-metastatic osteosarcoma (OS) of the extremities in terms of cure rate and quality of life for survivors. While twenty years ago, in spite of amputation, most patients with this tumour died, today about 3/4 of them are cured an amputation is avoided. These advances are due mainly to the development of effective adjuvant and neoadjuvant chemotherapeutic regimens. This review reports on the progress and controversies in the treatment of OS occurred with respect to the construct, experimental design and interpretation of the more important studies which led to these remarkable results.
| Original language | English |
|---|---|
| Pages (from-to) | 52-65 |
| Number of pages | 14 |
| Journal | FORUM - Trends in Experimental and Clinical Medicine |
| Volume | 4 |
| Issue number | 1 |
| Publication status | Published - 1994 |
Fingerprint
ASJC Scopus subject areas
- Medicine(all)
Cite this
An analysis of factors influencing treatment options in osteosarcoma. / Bacci, G.; Picci, P.
In: FORUM - Trends in Experimental and Clinical Medicine, Vol. 4, No. 1, 1994, p. 52-65.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - An analysis of factors influencing treatment options in osteosarcoma
AU - Bacci, G.
AU - Picci, P.
PY - 1994
Y1 - 1994
N2 - During the past twenty years dramatic advances have been made in the treatment of non-metastatic osteosarcoma (OS) of the extremities in terms of cure rate and quality of life for survivors. While twenty years ago, in spite of amputation, most patients with this tumour died, today about 3/4 of them are cured an amputation is avoided. These advances are due mainly to the development of effective adjuvant and neoadjuvant chemotherapeutic regimens. This review reports on the progress and controversies in the treatment of OS occurred with respect to the construct, experimental design and interpretation of the more important studies which led to these remarkable results.
AB - During the past twenty years dramatic advances have been made in the treatment of non-metastatic osteosarcoma (OS) of the extremities in terms of cure rate and quality of life for survivors. While twenty years ago, in spite of amputation, most patients with this tumour died, today about 3/4 of them are cured an amputation is avoided. These advances are due mainly to the development of effective adjuvant and neoadjuvant chemotherapeutic regimens. This review reports on the progress and controversies in the treatment of OS occurred with respect to the construct, experimental design and interpretation of the more important studies which led to these remarkable results.
UR - http://www.scopus.com/inward/record.url?scp=0028212560&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028212560&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0028212560
VL - 4
SP - 52
EP - 65
JO - FORUM - Trends in Experimental and Clinical Medicine
JF - FORUM - Trends in Experimental and Clinical Medicine
SN - 1121-8142
IS - 1
ER -