An approach using lecithin treatment for olivopontocerebellar atrophies

G. Finocchiaro, S. Di Donato, M. Madonna, R. Fusi, H. Ladinsky, S. Consolo

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A therapeutic trial with two different lecithins, with 32 and 7% phosphatidylcholine respectively, was performed for 3 months on 11 patients with clinical diagnosis of dominant, recessive and sporadic olivopontocerebellar atrophies. The correlation between plasma choline levels and the clinical picture shows a clinical worsening with very high choline levels and a slight improvement with smaller increases of plasma choline levels. The possible role in these disorders of phosphatidylcholine and linoleic acid - both present in lecithin - is discussed, with relationship to these findings.

Original languageEnglish
Pages (from-to)414-421
Number of pages8
JournalEuropean Neurology
Volume24
Issue number6
DOIs
Publication statusPublished - 1985

Fingerprint

Olivopontocerebellar Atrophies
Lecithins
Choline
Phosphatidylcholines
Linoleic Acid
Therapeutics

Keywords

  • Choline
  • Lecithin
  • Olivopontocerebellar atrophy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Finocchiaro, G., Di Donato, S., Madonna, M., Fusi, R., Ladinsky, H., & Consolo, S. (1985). An approach using lecithin treatment for olivopontocerebellar atrophies. European Neurology, 24(6), 414-421. https://doi.org/10.1159/000115835

An approach using lecithin treatment for olivopontocerebellar atrophies. / Finocchiaro, G.; Di Donato, S.; Madonna, M.; Fusi, R.; Ladinsky, H.; Consolo, S.

In: European Neurology, Vol. 24, No. 6, 1985, p. 414-421.

Research output: Contribution to journalArticle

Finocchiaro, G, Di Donato, S, Madonna, M, Fusi, R, Ladinsky, H & Consolo, S 1985, 'An approach using lecithin treatment for olivopontocerebellar atrophies', European Neurology, vol. 24, no. 6, pp. 414-421. https://doi.org/10.1159/000115835
Finocchiaro, G. ; Di Donato, S. ; Madonna, M. ; Fusi, R. ; Ladinsky, H. ; Consolo, S. / An approach using lecithin treatment for olivopontocerebellar atrophies. In: European Neurology. 1985 ; Vol. 24, No. 6. pp. 414-421.
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