An artificial model for double mixed agglutination reaction

M. Ferrarini, A. S. Kelus

Research output: Contribution to journalArticlepeer-review


An artificial model for double mixed agglutination was worked out using baby hamster kidney cells (BHK) from a continuous culture and sheep and guinea-pig erythrocytes as indicators. The rabbit IgG of different allotypes was built into the surface of the BHK cells by bis-diazotized benzidine; the erythrocytes were coated with rabbit antibodies (mainly IgG) to them. The anti-erythrocyte antibodies used had a defined allotypic structure. Reaction between BHK cells with rabbit IgG determinants and the 2 types (sheep and guinea-pig) of indicator cell has been demonstrated.

Original languageEnglish
Pages (from-to)640-647
Number of pages8
JournalInternational Archives of Allergy and Immunology
Issue number5-6
Publication statusPublished - 1970

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy


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