Valutazione della rigenerazione neuronale nelle anastomosi nervose mediante sistemi tutoriali sintetici, biologici e somministrazione di insulina: studio sperimentale sul ratto.

Translated title of the contribution: An assessment of neuronal regeneration in neural anastomoses by synthetic guide and biological systems and insulin administration: an experimental study in the rat

R. Vellucci, L. Toppi, L. G. Capuano, P. Picozzi, A. Bove, A. Pasciuto, S. Lucci, L. Corbellini

Research output: Contribution to journalArticle


The synthetic and biological nerve guide regeneration gives interesting perspective of use in making artificial conduits for peripheral nerve reconstruction. In sixty Wistar rats, under general anesthesia and with microsurgical technique, the ischiatic nerve was isolated. On the right side a segment of the nerve was removed in order to create a 10 mm gap. The defect then repaired using the conduit. Control were performed at 20, 90, 180 days and consisted in histological microscopy and electromyography investigation. The regeneration of the nerve fibers in the lumen of the conduit was not significantly different on the contralateral nerve limb.

Original languageItalian
Pages (from-to)316-324
Number of pages9
JournalGiornale di Chirurgia
Issue number6-7
Publication statusPublished - Jun 1999


ASJC Scopus subject areas

  • Surgery

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