An asymmetry in past and future mental time travel following vmPFC damage

Elisa Ciaramelli, Filomena Anelli, Francesca Frassinetti

Research output: Contribution to journalArticlepeer-review

Abstract

The role of ventromedial prefrontal cortex (vmPFC) in mental time travel toward the past and the future is debated. Here, patients with focal lesions to the vmPFC and brain-damaged and healthy controls mentally projected themselves to a past, present or future moment of subjective time (self-projection) and classified a series of events as past or future relative to the adopted temporal self-location (self-reference). We found that vmPFC patients were selectively impaired in projecting themselves to the future and in recognizing relative-future events. These findings indicate that vmPFC damage hinders the mental processing of and movement toward future events, pointing to a prominent, multifaceted role of vmPFC in future-oriented mental time travel.

Original languageEnglish
Pages (from-to)315-325
Number of pages11
JournalSocial Cognitive and Affective Neuroscience
Volume16
Issue number3
DOIs
Publication statusPublished - Mar 5 2021

Keywords

  • Adult
  • Aged
  • Brain Injuries/psychology
  • Female
  • Humans
  • Imagination
  • Male
  • Memory, Episodic
  • Middle Aged
  • Prefrontal Cortex/injuries

Fingerprint

Dive into the research topics of 'An asymmetry in past and future mental time travel following vmPFC damage'. Together they form a unique fingerprint.

Cite this