An easy and reproducible parameter for the assessment of the pressure gradient in patients with aortic stenosis disease: A magnetic resonance study

Valentina Valenti, Sebastiano Sciarretta, Matt Levin, Leon Shubayev, Sophia Edelstein, Mohammad I. Zia, Speranza Rubattu, Massimo Volpe, Seth Uretsky, Steven D. Wolff

Research output: Contribution to journalArticle

Abstract

Aim: Cardiovascular magnetic resonance (CMR) has been increasingly used as an alternative method to evaluate the severity of aortic stenosis. The aim of our study was to evaluate whether the indirect measurement of the aortic gradient (Calc-PG), derived from Gorlin's formula, is a reproducible parameter for gradient assessment. Then, we evaluated if this parameter is correlated with left ventricular hypertrophy, considered as a marker of severity of aortic stenosis, better than phase-contrast sequences-derived pressure gradient (PC-PG) and aortic valve area. Methods: Forty-one patients with isolated aortic stenosis underwent CMR. Calc-PG was obtained from the formula (cardiac output/aortic valve area)2, and it was compared to PC-PG. Results: We found that the Calc-PG has higher correlation with left ventricle mass than PC-PG (r2 0.44, p2 0.26, p

Original languageEnglish
Pages (from-to)369-376
Number of pages8
JournalJournal of Cardiology
Volume65
Issue number5
DOIs
Publication statusPublished - May 1 2015

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Aortic Diseases
Aortic Valve Stenosis
Magnetic Resonance Spectroscopy
Aortic Valve
Pressure
Left Ventricular Hypertrophy
Cardiac Output
Heart Ventricles

Keywords

  • Aortic stenosis
  • Cardiac magnetic resonance
  • Gorlin's formula
  • Hakki's formula
  • Pressure gradient

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

An easy and reproducible parameter for the assessment of the pressure gradient in patients with aortic stenosis disease : A magnetic resonance study. / Valenti, Valentina; Sciarretta, Sebastiano; Levin, Matt; Shubayev, Leon; Edelstein, Sophia; Zia, Mohammad I.; Rubattu, Speranza; Volpe, Massimo; Uretsky, Seth; Wolff, Steven D.

In: Journal of Cardiology, Vol. 65, No. 5, 01.05.2015, p. 369-376.

Research output: Contribution to journalArticle

Valenti, Valentina ; Sciarretta, Sebastiano ; Levin, Matt ; Shubayev, Leon ; Edelstein, Sophia ; Zia, Mohammad I. ; Rubattu, Speranza ; Volpe, Massimo ; Uretsky, Seth ; Wolff, Steven D. / An easy and reproducible parameter for the assessment of the pressure gradient in patients with aortic stenosis disease : A magnetic resonance study. In: Journal of Cardiology. 2015 ; Vol. 65, No. 5. pp. 369-376.
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AU - Zia, Mohammad I.

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