Abstract
A facile and practical synthesis of enantiomerically pure (L) or (D)-threo-Ifenprodil was accomplished from (1S, 2S)- and (1R, 2R)-threo-1-(p-nitrophenyl)-2-amino-propan-1, 3-diol via 3-phenylthio derivatives followed by Raney nickel reduction and conversion of the aromatic amine into phenol.
| Original language | English |
|---|---|
| Pages (from-to) | 3543-3553 |
| Number of pages | 11 |
| Journal | Synthetic Communications |
| Volume | 30 |
| Issue number | 19 |
| Publication status | Published - 2000 |
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ASJC Scopus subject areas
- Organic Chemistry
Cite this
Mantegani, S., Arlandini, E., Brambilla, E., Cremonesi, P., & Varasi, M. (2000). An easy entry to (1S, 2S) and (1R, 2R)-threo-Ifenprodil. Synthetic Communications, 30(19), 3543-3553.