An elastic computerized brain atlas for the analysis of clinical PET/SPET data

Giovanna Rizzo, Maria Carla Gilardi, Anna Prinster, Franco Grassi, Giuseppe Scotti, Sergio Cerutti, Ferruccio Fazio

Research output: Contribution to journalArticlepeer-review

Abstract

An elastic computerized brain atlas was developed for the analysis of positron emission tomography/single-photon emission tomography (PET/SPET) data. It consists of a set of digital anatomical contours and a template of regions of interest, schematically describing the brain, derived from a currently used anatomical/functional brain atlas. A warping algorithm, matching equivalent contours, was implemented to elastically fit the atlas to individual brain images. The elastic computerized brain atlas was applied to representative magnetic resonance imaging (MRI)-PET/SPET studies, MRI providing the anatomical information used by the matching procedure. The atlas is suited for clinical use in a nuclear medicine environment.

Original languageEnglish
Pages (from-to)1313-1318
Number of pages6
JournalEuropean Journal Of Nuclear Medicine
Volume22
Issue number11
DOIs
Publication statusPublished - Nov 1995

Keywords

  • Brain atlas
  • Emission tomography
  • Magnetic resonance imaging
  • Warping

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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