An electrophysiological contribution to the study of language lateralization and prognosis of aphasia

Andrea Cobianchi, Valentina Dall'Armi, Salvatore Giaquinto

Research output: Contribution to journalArticle

Abstract

The study is aimed at identifying hemispheric language dominance in both the right-handed and left-handed participants. Eighteen right-handed and 18 left-handed young volunteers were invited to listen for 80 times to a 720ms duration Italian word. Signals from 16 electrodes were averaged and displayed both as traces and maps. When the word was delivered to the participant, a positive component at 340ms was recorded, following the N100-P200 complex. The potential was significantly lateralized to the left hemisphere in 50% of the right-handers. The left-handed group was less homogeneous. Six out of 18 participants (33%) had a right lateralization, six participants (33%) had the positive potential shifted to the left hemisphere. Finally, the remaining participants had a bilateral representation. The maps show that there are no two participants alike, independently of either sex or handedness. A 300Hz tone of the same duration failed to evoke the P340. Results indicate the utility of event-related potentials in studying the language processing. The possibility to identify cortical localization permits a better prognosis of acquired aphasia. The method is relatively cheap and noninvasive. Application is suggested in those participants who are at risk of stroke or in patients to be submitted to a neurosurgical intervention nearby possible language areas.

Original languageEnglish
Pages (from-to)134-141
Number of pages8
JournalInternational Journal of Rehabilitation Research
Volume33
Issue number2
DOIs
Publication statusPublished - Jun 2010

Fingerprint

Aphasia
Language
Functional Laterality
Evoked Potentials
Volunteers
Electrodes
Stroke

Keywords

  • Cerebral dominance
  • Electrophysiology
  • Left-handedness
  • Rehabilitation

ASJC Scopus subject areas

  • Rehabilitation
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

An electrophysiological contribution to the study of language lateralization and prognosis of aphasia. / Cobianchi, Andrea; Dall'Armi, Valentina; Giaquinto, Salvatore.

In: International Journal of Rehabilitation Research, Vol. 33, No. 2, 06.2010, p. 134-141.

Research output: Contribution to journalArticle

Cobianchi, Andrea ; Dall'Armi, Valentina ; Giaquinto, Salvatore. / An electrophysiological contribution to the study of language lateralization and prognosis of aphasia. In: International Journal of Rehabilitation Research. 2010 ; Vol. 33, No. 2. pp. 134-141.
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