An epidemiological survey of vulvovaginal candidiasis in Italy

Salvatore Corsello, Arsenio Spinillo, Giuseppe Osnengo, Carlo Penna, Secondo Guaschino, Anna Beltrame, Nicola Blasi, Antonio Festa, E. Cammarata, G. Tempera, C. Bergante, D. Biancheri, P. Bordonaro, M. G. Fallani, M. Fambrini, M. Busetti, C. Campello, D. De Santo, F. De Seta, F. PanerariC. Strazzanti, I. Foresti, A. Matteelli, V. Borraccino, G. Caggiano, A. Lepera, M. T. Montagna, E. Noya, S. Schönauer, B. Dente, A. Ferrari, P. Dang

Research output: Contribution to journalArticle

Abstract

Eight Italian hospital or University gynecology clinics participated in a prospective survey of patients with culture-confirmed symptomatic vulvovaginal candidiasis (VVC) (October 1999 to March 2001). Of 1138 patients recruited in the study, 931 were evaluable. A recent history of VVC was documented in 43.5% patients (358/823) with a mean number of 2.9±2.7 episodes per patient (N=302). A total of 77 patients (10.0%) had a history of recurrent VVC (four and more episodes in a 12-month period). The most frequent associated factors were related to life style: synthetic fabric underwear, vaginal douching and bike, training bike and motorbike (about 1/3 each). Oral contraception was found in 20.8% patients, recent antibiotic use in 15.9% patients, current pregnancy concerned 10.3% patients while 3.4% patients were taking hormonal replacement therapy. Diabetes, corticosteroids or HIV were rarely encountered. Yeast was documented by direct microscopy in 78.3% patients (448/572). A positive culture was obtained in 98.3% patients (909/925). Candida albicans was the predominant species (77.1%), followed by Candida glabrata (14.6%) and Candida krusei (4.0%). With the exception of one center with a lower proportion of C. albicans, this latter represented between 75 and 85% of the isolates. Overall, this study confirmed the preponderant role played by C. albicans in either sporadic and recurrent VVC.

Original languageEnglish
Pages (from-to)66-72
Number of pages7
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Volume110
Issue number1
DOIs
Publication statusPublished - Sep 10 2003

Keywords

  • Candida
  • HIV
  • Vulvovaginal candidiasis

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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  • Cite this

    Corsello, S., Spinillo, A., Osnengo, G., Penna, C., Guaschino, S., Beltrame, A., Blasi, N., Festa, A., Cammarata, E., Tempera, G., Bergante, C., Biancheri, D., Bordonaro, P., Fallani, M. G., Fambrini, M., Busetti, M., Campello, C., De Santo, D., De Seta, F., ... Dang, P. (2003). An epidemiological survey of vulvovaginal candidiasis in Italy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 110(1), 66-72. https://doi.org/10.1016/S0301-2115(03)00096-4