This study was performed on 4 batchet of adult rabbits in our Experimental Laboratory. First batch: the After Discharges (AD) produced by stimulating the amygdala inhibited the cycle of excitability of the amygdala only when able to recruit the reticular formation (FR) causing a generalized discharge of polyspike-wave. On the basis of this observation we were able to formulate a suggestive hypothesis regarding the role of GM seizures in emotional homeostasis. In the following batches, application of excitatory substances such as kainic acid in the intralaminar thalamus (Aspecific Defacilitatory System) and into che central grey matter (CGM) made it posible, by studying the AD produced by stimulation of the intralaminar thalamus, to assess the implications of the thresholds of each single aspecific system in the various clinical forms of epileptic syndrome. Lastly, the value of the vectorial EEG for identification of the temporal source in generalized discharge is discussed.
|Translated title of the contribution||An experimental contribution on the temporal lobe and epilepsy: The role of diffuse aspecific systems|
|Number of pages||5|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 1996|
ASJC Scopus subject areas
- Clinical Neurology