An experimental study on human articular cartilage permeability

F. Boschetti, C. Miotti, F. Massi, M. Colombo, V. Quaglini, G. M. Peretti, R. Pietrabissa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The permeability of cartilage contributes to many tissue functions, like the transport of nutrients to chondrocytes, the ability to carry high loads, and the maintenance of a lubricating fluid film between opposing articular surfaces. We measured in vitro the permeability of the human lateral tibial plateau cartilage through its depth, by measuring the fluid flow induced by an applied pressure gradient; values range from 1.38×10-16 to 8.01×10-16 m4/Ns, showing a decrease with increasing pressure in every layer and a decrease with depth for every level of applied pressure difference. We also extrapolated the permeability values from creep tests performed on the same samples.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages2581-2582
Number of pages2
Volume3
Publication statusPublished - 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Other

OtherProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS)
CountryUnited States
CityHouston, TX
Period10/23/0210/26/02

Keywords

  • Biomechanical testing
  • Cartilage
  • Permeability

ASJC Scopus subject areas

  • Bioengineering

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