Studio sperimentale sulla variabilita di risposta cutanea all'applicazione di acido glicolico

Translated title of the contribution: An experimental study on the variability of skin response to glycolic acid application

M. Monti, S. Motta, S. Sesana, F. Sacrini, E. Parolari, A. Caretti

Research output: Contribution to journalArticlepeer-review

Abstract

Glycolic acid full-strength concentration is widely used as caustic substance in superficial chemical peeling. In this application the safety of glycolic acid is considered high. This substance is commercially available in different concentrations and formulations; the latterones are not justified by experimental study. For this reason some parameters, that can modify the peeling strength, have been experimentally tested in this paper. The considered parameters are: the mean concentration of glycolic acid that produces erythema, the interindividual sensitivity, the role of skin delipidization, the glycolic acid solution pH variation, the artificial thinning of the stratum corneum and the surface-active agent addition to glycolic acid solution. This experimental study reveals that there is extreme variability in the skin response to glycolic acid and that the peeling strength may be modified by changing the considered parameters. The results obtained are useful to understand glycolic acid activity and to choose the right concentration and formulation in clinical practice.

Translated title of the contributionAn experimental study on the variability of skin response to glycolic acid application
Original languageItalian
Pages (from-to)59-63
Number of pages5
JournalGiornale Italiano di Dermatologia e Venereologia
Volume132
Issue number1
Publication statusPublished - 1997

ASJC Scopus subject areas

  • Dermatology

Fingerprint

Dive into the research topics of 'An experimental study on the variability of skin response to glycolic acid application'. Together they form a unique fingerprint.

Cite this