An eye-tracking controlled neuropsychological battery for cognitive assessment in neurological diseases

Barbara Poletti, Laura Carelli, Federica Solca, Annalisa Lafronza, Elisa Pedroli, Andrea Faini, Stefano Zago, Nicola Ticozzi, Andrea Ciammola, Claudia Morelli, Paolo Meriggi, Pietro Cipresso, Dorothée Lulé, Albert C Ludolph, Giuseppe Riva, Vincenzo Silani

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Traditional cognitive assessment in neurological conditions involving physical disability is often prevented by the presence of verbal-motor impairment; to date, an extensive motor-verbal-free neuropsychological battery is not available for such purposes. We adapted a set of neuropsychological tests, assessing language, attentional abilities, executive functions and social cognition, for eye-tracking (ET) control, and explored its feasibility in a sample of healthy participants. Thirty healthy subjects performed a neuropsychological assessment, using an ET-based neuropsychological battery, together with standard "paper and pencil" cognitive measures for frontal (Frontal Assessment Battery-FAB) and working memory abilities (Digit Sequencing Task) and for global cognitive efficiency (Montreal Cognitive Assessment-MoCA). Psychological measures of anxiety (State-Trait Anxiety Inventory-Y-STAI-Y) and depression (Beck Depression Inventory-BDI) were also collected, and a usability questionnaire was administered. Significant correlations were observed between the "paper and pencil" screening of working memory abilities and the ET-based neuropsychological measures. The ET-based battery also correlated with the MoCA, while poor correlations were observed with the FAB. Usability aspects were found to be influenced by both working memory abilities and psychological components. The ET-based neuropsychological battery developed could provide an extensive assessment of cognitive functions, allowing participants to perform tasks independently from the integrity of motor or verbal channels. Further studies will be aimed at investigating validity and usability components in neurological populations with motor-verbal impairments.

Original languageEnglish
Pages (from-to)595-603
Number of pages9
JournalNeurological Sciences
Volume38
Issue number4
DOIs
Publication statusPublished - Apr 2017

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Short-Term Memory
Cognition
Healthy Volunteers
Anxiety
Depression
Psychology
Equipment and Supplies
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Executive Function
Language
Efficiency
Population

Keywords

  • Attention
  • Cognition
  • Executive Function
  • Eye Movement Measurements
  • Feasibility Studies
  • Female
  • Humans
  • Language
  • Language Tests
  • Male
  • Memory, Short-Term
  • Middle Aged
  • Nervous System Diseases
  • Neuropsychological Tests
  • Social Behavior
  • Socioeconomic Factors
  • Evaluation Studies
  • Journal Article

Cite this

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title = "An eye-tracking controlled neuropsychological battery for cognitive assessment in neurological diseases",
abstract = "Traditional cognitive assessment in neurological conditions involving physical disability is often prevented by the presence of verbal-motor impairment; to date, an extensive motor-verbal-free neuropsychological battery is not available for such purposes. We adapted a set of neuropsychological tests, assessing language, attentional abilities, executive functions and social cognition, for eye-tracking (ET) control, and explored its feasibility in a sample of healthy participants. Thirty healthy subjects performed a neuropsychological assessment, using an ET-based neuropsychological battery, together with standard {"}paper and pencil{"} cognitive measures for frontal (Frontal Assessment Battery-FAB) and working memory abilities (Digit Sequencing Task) and for global cognitive efficiency (Montreal Cognitive Assessment-MoCA). Psychological measures of anxiety (State-Trait Anxiety Inventory-Y-STAI-Y) and depression (Beck Depression Inventory-BDI) were also collected, and a usability questionnaire was administered. Significant correlations were observed between the {"}paper and pencil{"} screening of working memory abilities and the ET-based neuropsychological measures. The ET-based battery also correlated with the MoCA, while poor correlations were observed with the FAB. Usability aspects were found to be influenced by both working memory abilities and psychological components. The ET-based neuropsychological battery developed could provide an extensive assessment of cognitive functions, allowing participants to perform tasks independently from the integrity of motor or verbal channels. Further studies will be aimed at investigating validity and usability components in neurological populations with motor-verbal impairments.",
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author = "Barbara Poletti and Laura Carelli and Federica Solca and Annalisa Lafronza and Elisa Pedroli and Andrea Faini and Stefano Zago and Nicola Ticozzi and Andrea Ciammola and Claudia Morelli and Paolo Meriggi and Pietro Cipresso and Doroth{\'e}e Lul{\'e} and Ludolph, {Albert C} and Giuseppe Riva and Vincenzo Silani",
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T1 - An eye-tracking controlled neuropsychological battery for cognitive assessment in neurological diseases

AU - Poletti, Barbara

AU - Carelli, Laura

AU - Solca, Federica

AU - Lafronza, Annalisa

AU - Pedroli, Elisa

AU - Faini, Andrea

AU - Zago, Stefano

AU - Ticozzi, Nicola

AU - Ciammola, Andrea

AU - Morelli, Claudia

AU - Meriggi, Paolo

AU - Cipresso, Pietro

AU - Lulé, Dorothée

AU - Ludolph, Albert C

AU - Riva, Giuseppe

AU - Silani, Vincenzo

PY - 2017/4

Y1 - 2017/4

N2 - Traditional cognitive assessment in neurological conditions involving physical disability is often prevented by the presence of verbal-motor impairment; to date, an extensive motor-verbal-free neuropsychological battery is not available for such purposes. We adapted a set of neuropsychological tests, assessing language, attentional abilities, executive functions and social cognition, for eye-tracking (ET) control, and explored its feasibility in a sample of healthy participants. Thirty healthy subjects performed a neuropsychological assessment, using an ET-based neuropsychological battery, together with standard "paper and pencil" cognitive measures for frontal (Frontal Assessment Battery-FAB) and working memory abilities (Digit Sequencing Task) and for global cognitive efficiency (Montreal Cognitive Assessment-MoCA). Psychological measures of anxiety (State-Trait Anxiety Inventory-Y-STAI-Y) and depression (Beck Depression Inventory-BDI) were also collected, and a usability questionnaire was administered. Significant correlations were observed between the "paper and pencil" screening of working memory abilities and the ET-based neuropsychological measures. The ET-based battery also correlated with the MoCA, while poor correlations were observed with the FAB. Usability aspects were found to be influenced by both working memory abilities and psychological components. The ET-based neuropsychological battery developed could provide an extensive assessment of cognitive functions, allowing participants to perform tasks independently from the integrity of motor or verbal channels. Further studies will be aimed at investigating validity and usability components in neurological populations with motor-verbal impairments.

AB - Traditional cognitive assessment in neurological conditions involving physical disability is often prevented by the presence of verbal-motor impairment; to date, an extensive motor-verbal-free neuropsychological battery is not available for such purposes. We adapted a set of neuropsychological tests, assessing language, attentional abilities, executive functions and social cognition, for eye-tracking (ET) control, and explored its feasibility in a sample of healthy participants. Thirty healthy subjects performed a neuropsychological assessment, using an ET-based neuropsychological battery, together with standard "paper and pencil" cognitive measures for frontal (Frontal Assessment Battery-FAB) and working memory abilities (Digit Sequencing Task) and for global cognitive efficiency (Montreal Cognitive Assessment-MoCA). Psychological measures of anxiety (State-Trait Anxiety Inventory-Y-STAI-Y) and depression (Beck Depression Inventory-BDI) were also collected, and a usability questionnaire was administered. Significant correlations were observed between the "paper and pencil" screening of working memory abilities and the ET-based neuropsychological measures. The ET-based battery also correlated with the MoCA, while poor correlations were observed with the FAB. Usability aspects were found to be influenced by both working memory abilities and psychological components. The ET-based neuropsychological battery developed could provide an extensive assessment of cognitive functions, allowing participants to perform tasks independently from the integrity of motor or verbal channels. Further studies will be aimed at investigating validity and usability components in neurological populations with motor-verbal impairments.

KW - Attention

KW - Cognition

KW - Executive Function

KW - Eye Movement Measurements

KW - Feasibility Studies

KW - Female

KW - Humans

KW - Language

KW - Language Tests

KW - Male

KW - Memory, Short-Term

KW - Middle Aged

KW - Nervous System Diseases

KW - Neuropsychological Tests

KW - Social Behavior

KW - Socioeconomic Factors

KW - Evaluation Studies

KW - Journal Article

U2 - 10.1007/s10072-016-2807-3

DO - 10.1007/s10072-016-2807-3

M3 - Article

VL - 38

SP - 595

EP - 603

JO - Neurological Sciences

JF - Neurological Sciences

SN - 1590-1874

IS - 4

ER -