An HPTLC Approach to Quantitative Determination of Some Prostaglandins in Serum: Study in Normal and Asthmatic Subjects

P. Bruno, M. Carino, M. Caselli, L. Macchia, A. Fornelli, A. Traini, L. Ambrosi, A. Tursi

Research output: Contribution to journalArticle

Abstract

A modified HPTLC technique was applied in investigating venous peripheral blood concentrations of PGE1, PGE2, PGFIα, PGF2α, PGA1 and PGA2 in three subjects with occupational asthma, undergoing specific bronchial challenge test with chemical sensitizers, as well as in two control subjects, exposed to the same test. The findings obtained show that the technique employed in our study is quite suitable and could be useful to acquire more information on some biochemical events occurring during asthmatic responses to bronchial challenge.

Original languageEnglish
Pages (from-to)1155-1164
Number of pages10
JournalAnalytical Letters
Volume21
Issue number7
DOIs
Publication statusPublished - 1988

Keywords

  • Alkaline Persulfates
  • HPTLC
  • Isocyanates
  • Occupational Asthma
  • Prostaglandins

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Analytical Chemistry
  • Electrochemistry
  • Spectroscopy
  • Biochemistry, medical
  • Biochemistry, Genetics and Molecular Biology(all)

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