Abstract
Increasingly complex vascular reconstructions and emerging endovascular therapeutic modalities have stimulated the need for improved vascular imaging. To determine the feasibility of in vivo intravascular ultrasound, a miniature probe 1 mm in diameter with a 25 MHz center frequency was used to obtain two-dimensional, 360-degree cross-sectional images. In sheep, 14 superficial femoral arteries were imaged at different sites, and a portion of each vessel was resected for immediate in vitro imaging and histologic examination. In vivo images clearly showed the intima, media, and adventitia of the vessel wall as well as the lumen-intima and mediaadventitia interfaces. There was a significant correlation in measured lumen area between resected artery ultrasound images and histologic sections. We conclude that intravascular ultrasound can produce high-resolution dynamic images that demonstrate vessel wall architecture and allow precise calculation of lumen area.
| Original language | English |
|---|---|
| Pages (from-to) | 142-145 |
| Number of pages | 4 |
| Journal | American Journal of Surgery |
| Volume | 158 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1989 |
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ASJC Scopus subject areas
- Surgery
Cite this
An in vivo feasibility study of intravascular ultrasound imaging. / Neville, Richard F.; Bartorelli, Antonio L.; Sidawy, Anton N.; Almagor, Yaron; Potkin, Benjamin; Leon, Martin B.
In: American Journal of Surgery, Vol. 158, No. 2, 1989, p. 142-145.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - An in vivo feasibility study of intravascular ultrasound imaging
AU - Neville, Richard F.
AU - Bartorelli, Antonio L.
AU - Sidawy, Anton N.
AU - Almagor, Yaron
AU - Potkin, Benjamin
AU - Leon, Martin B.
PY - 1989
Y1 - 1989
N2 - Increasingly complex vascular reconstructions and emerging endovascular therapeutic modalities have stimulated the need for improved vascular imaging. To determine the feasibility of in vivo intravascular ultrasound, a miniature probe 1 mm in diameter with a 25 MHz center frequency was used to obtain two-dimensional, 360-degree cross-sectional images. In sheep, 14 superficial femoral arteries were imaged at different sites, and a portion of each vessel was resected for immediate in vitro imaging and histologic examination. In vivo images clearly showed the intima, media, and adventitia of the vessel wall as well as the lumen-intima and mediaadventitia interfaces. There was a significant correlation in measured lumen area between resected artery ultrasound images and histologic sections. We conclude that intravascular ultrasound can produce high-resolution dynamic images that demonstrate vessel wall architecture and allow precise calculation of lumen area.
AB - Increasingly complex vascular reconstructions and emerging endovascular therapeutic modalities have stimulated the need for improved vascular imaging. To determine the feasibility of in vivo intravascular ultrasound, a miniature probe 1 mm in diameter with a 25 MHz center frequency was used to obtain two-dimensional, 360-degree cross-sectional images. In sheep, 14 superficial femoral arteries were imaged at different sites, and a portion of each vessel was resected for immediate in vitro imaging and histologic examination. In vivo images clearly showed the intima, media, and adventitia of the vessel wall as well as the lumen-intima and mediaadventitia interfaces. There was a significant correlation in measured lumen area between resected artery ultrasound images and histologic sections. We conclude that intravascular ultrasound can produce high-resolution dynamic images that demonstrate vessel wall architecture and allow precise calculation of lumen area.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024399490&partnerID=8YFLogxK
U2 - 10.1016/0002-9610(89)90363-2
DO - 10.1016/0002-9610(89)90363-2
M3 - Article
VL - 158
SP - 142
EP - 145
JO - American Journal of Surgery
JF - American Journal of Surgery
SN - 0002-9610
IS - 2
ER -