An in vivo feasibility study of intravascular ultrasound imaging

Richard F. Neville, Antonio L. Bartorelli, Anton N. Sidawy, Yaron Almagor, Benjamin Potkin, Martin B. Leon

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Increasingly complex vascular reconstructions and emerging endovascular therapeutic modalities have stimulated the need for improved vascular imaging. To determine the feasibility of in vivo intravascular ultrasound, a miniature probe 1 mm in diameter with a 25 MHz center frequency was used to obtain two-dimensional, 360-degree cross-sectional images. In sheep, 14 superficial femoral arteries were imaged at different sites, and a portion of each vessel was resected for immediate in vitro imaging and histologic examination. In vivo images clearly showed the intima, media, and adventitia of the vessel wall as well as the lumen-intima and mediaadventitia interfaces. There was a significant correlation in measured lumen area between resected artery ultrasound images and histologic sections. We conclude that intravascular ultrasound can produce high-resolution dynamic images that demonstrate vessel wall architecture and allow precise calculation of lumen area.

Original languageEnglish
Pages (from-to)142-145
Number of pages4
JournalAmerican Journal of Surgery
Volume158
Issue number2
DOIs
Publication statusPublished - 1989

Fingerprint

Feasibility Studies
Blood Vessels
Ultrasonography
Adventitia
Femoral Artery
Sheep
Arteries
Therapeutics
In Vitro Techniques

ASJC Scopus subject areas

  • Surgery

Cite this

An in vivo feasibility study of intravascular ultrasound imaging. / Neville, Richard F.; Bartorelli, Antonio L.; Sidawy, Anton N.; Almagor, Yaron; Potkin, Benjamin; Leon, Martin B.

In: American Journal of Surgery, Vol. 158, No. 2, 1989, p. 142-145.

Research output: Contribution to journalArticle

Neville, Richard F. ; Bartorelli, Antonio L. ; Sidawy, Anton N. ; Almagor, Yaron ; Potkin, Benjamin ; Leon, Martin B. / An in vivo feasibility study of intravascular ultrasound imaging. In: American Journal of Surgery. 1989 ; Vol. 158, No. 2. pp. 142-145.
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