An information aid for newly diagnosed multiple sclerosis patients improves disease knowledge and satisfaction with care

A. Solari, V. Martinelli, M. Trojano, A. Lugaresi, F. Granella, A. Giordano, M. Messmer Uccelli, R. D'Alessandro, E. Pucci, P. Confalonieri, C. Borreani

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Patients report information deficits in the period surrounding diagnosis of multiple sclerosis (MS). We assessed the effectiveness of an add-on information aid for newly diagnosed MS patients. Methods: We randomly assigned 120 newly diagnosed MS patients from five Italian centres to diagnosis disclosure (current practice at the centre) or current practice plus information aid (ISRCTN81072971). The information aid consisted of a personal interview with a physician using a navigable compact disc and a take-home booklet. The primary composite endpoint was score in the highest tertile of MS knowledge and satisfaction with care questionnaires. Other endpoints were safety; treatment adherence; extra contacts/consultations; switching of care centre; and changes in Hospital Anxiety and Depression Scale and Control Preference Scale scores. Results: At 1 month, 30/60 intervention and 8/60 control patients achieved the primary endpoint (odds ratio [OR] 6.5, 95% CI 2.6-16.0; p <0.001; number needed to treat [NNT] 3). Figures at 6 months were 26/60 intervention and 11/60 control patients (OR 3.4, 95% CI 1.5-7.8; p = 0.04; NNT 4). There were no adverse events. No significant treatment effects were seen on secondary outcomes. Conclusion: The information aid was safe and significantly associated with attainment of the primary outcome at 1 and 6 months.

Original languageEnglish
Pages (from-to)1393-1405
Number of pages13
JournalMultiple Sclerosis Journal
Volume16
Issue number11
DOIs
Publication statusPublished - Nov 2010

Keywords

  • complex health intervention
  • health knowledge
  • information aid
  • multiple sclerosis
  • patient satisfaction
  • randomized controlled trial

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Fingerprint Dive into the research topics of 'An information aid for newly diagnosed multiple sclerosis patients improves disease knowledge and satisfaction with care'. Together they form a unique fingerprint.

Cite this