An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients

N. Levy, J. Quinlan, K. El-Boghdadly, W. J. Fawcett, V. Agarwal, R. B. Bastable, F. J. Cox, H. D. de Boer, S. C. Dowdy, K. Hattingh, R. D. Knaggs, E. R. Mariano, P. Pelosi, M. J. Scott, D. N. Lobo, P. E. Macintyre

Research output: Contribution to journalArticlepeer-review

Abstract

This international multidisciplinary consensus statement was developed to provide balanced guidance on the safe peri-operative use of opioids in adults. An international panel of healthcare professionals evaluated the literature relating to postoperative opioid-related harm, including persistent postoperative opioid use; opioid-induced ventilatory impairment; non-medical opioid use; opioid diversion and dependence; and driving under the influence of prescription opioids. Recommended strategies to reduce harm include pre-operative assessment of the risk of persistent postoperative opioid use; use of an assessment of patient function rather than unidimensional pain scores alone to guide adequacy of analgesia; avoidance of long-acting (modified-release and transdermal patches) opioid formulations and combination analgesics; limiting the number of tablets prescribed at discharge; providing deprescribing advice; avoidance of automatic prescription refills; safe disposal of unused medicines; reducing the risk of opioid diversion; and better education of healthcare professionals, patients and carers. This consensus statement provides a framework for better prescribing practices that could help reduce the risk of postoperative opioid-related harm in adults.

Original languageEnglish
JournalAnaesthesia
DOIs
Publication statusAccepted/In press - 2020

Keywords

  • deprescribing
  • guidelines
  • opioid-induced ventilatory impairment
  • opioids
  • peri-operative
  • persistent postoperative opioid use

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Fingerprint Dive into the research topics of 'An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients'. Together they form a unique fingerprint.

Cite this