An international survey of chronic obstructive pulmonary disease in young adults according to GOLD stages

R. De Marco, S. Accordini, I. Cerveri, A. Corsico, J. Sunyer, F. Neukirch, N. Künzli, B. Leynaert, C. Janson, T. Gislason, P. Vermeire, C. Svanes, J. M. Anto, P. Burney

Research output: Contribution to journalArticle

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Abstract

Background: The recently published GOLD guidelines provide a new system for staging chronic obstructive pulmonary disease (COPD) from mild (stage I) to very severe (stage IV) and introduce a stage 0 (chronic cough and phlegm without airflow obstruction) that includes subjects "at risk" of developing the disease. Methods: In order to assess the prevalence of GOLD stages of COPD in high income countries and to evaluate their association with the known risk factors for airflow obstruction, data from the European Community Respiratory Health Survey on more than 18 000 young adults (20-44 years) were analysed. Results: The overall prevalence was 11.8% (95% CI 11.3 to 12.3) for stage 0, 2.5% (95% CI 2.2 to 2.7) for stage I, and 1.1% (95% CI 1.0 to 1.3) for stages II-III. Moderate to heavy smoking (≥ 5 pack years) was significantly associated with both stage 0 (relative risk ratio (RRR) = 4.15; 95% CI 3.55 to 4.84) and stages I+ (RRR = 4.09; 95% CI 3.17 to 5.26), while subjects with stages I+ COPD had a higher likelihood of giving up smoking (RRR = 1.39; 95% CI 1.04 to 1.86) than those with GOLD stage 0 (RRR = 1.05; 95% CI 0.86 to 1.27). Environmental tobacco smoke had the same degree of positive association in both groups. Respiratory infections in childhood and low socioeconomic class were significantly and homogeneously associated with both groups, whereas occupational exposure was significantly associated only with stage 0. All the GOLD stages showed a significantly higher percentage of healthcare resource users than healthy subjects (p

Original languageEnglish
Pages (from-to)120-125
Number of pages6
JournalThorax
Volume59
Issue number2
DOIs
Publication statusPublished - Feb 2004

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Chronic Obstructive Pulmonary Disease
Young Adult
Odds Ratio
Smoking
European Union
Occupational Exposure
Health Surveys
Cough
Smoke
Respiratory Tract Infections
Tobacco
Healthy Volunteers
Surveys and Questionnaires
Guidelines
Delivery of Health Care

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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An international survey of chronic obstructive pulmonary disease in young adults according to GOLD stages. / De Marco, R.; Accordini, S.; Cerveri, I.; Corsico, A.; Sunyer, J.; Neukirch, F.; Künzli, N.; Leynaert, B.; Janson, C.; Gislason, T.; Vermeire, P.; Svanes, C.; Anto, J. M.; Burney, P.

In: Thorax, Vol. 59, No. 2, 02.2004, p. 120-125.

Research output: Contribution to journalArticle

De Marco, R, Accordini, S, Cerveri, I, Corsico, A, Sunyer, J, Neukirch, F, Künzli, N, Leynaert, B, Janson, C, Gislason, T, Vermeire, P, Svanes, C, Anto, JM & Burney, P 2004, 'An international survey of chronic obstructive pulmonary disease in young adults according to GOLD stages', Thorax, vol. 59, no. 2, pp. 120-125. https://doi.org/10.1136/thorax.2003.011163
De Marco, R. ; Accordini, S. ; Cerveri, I. ; Corsico, A. ; Sunyer, J. ; Neukirch, F. ; Künzli, N. ; Leynaert, B. ; Janson, C. ; Gislason, T. ; Vermeire, P. ; Svanes, C. ; Anto, J. M. ; Burney, P. / An international survey of chronic obstructive pulmonary disease in young adults according to GOLD stages. In: Thorax. 2004 ; Vol. 59, No. 2. pp. 120-125.
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abstract = "Background: The recently published GOLD guidelines provide a new system for staging chronic obstructive pulmonary disease (COPD) from mild (stage I) to very severe (stage IV) and introduce a stage 0 (chronic cough and phlegm without airflow obstruction) that includes subjects {"}at risk{"} of developing the disease. Methods: In order to assess the prevalence of GOLD stages of COPD in high income countries and to evaluate their association with the known risk factors for airflow obstruction, data from the European Community Respiratory Health Survey on more than 18 000 young adults (20-44 years) were analysed. Results: The overall prevalence was 11.8{\%} (95{\%} CI 11.3 to 12.3) for stage 0, 2.5{\%} (95{\%} CI 2.2 to 2.7) for stage I, and 1.1{\%} (95{\%} CI 1.0 to 1.3) for stages II-III. Moderate to heavy smoking (≥ 5 pack years) was significantly associated with both stage 0 (relative risk ratio (RRR) = 4.15; 95{\%} CI 3.55 to 4.84) and stages I+ (RRR = 4.09; 95{\%} CI 3.17 to 5.26), while subjects with stages I+ COPD had a higher likelihood of giving up smoking (RRR = 1.39; 95{\%} CI 1.04 to 1.86) than those with GOLD stage 0 (RRR = 1.05; 95{\%} CI 0.86 to 1.27). Environmental tobacco smoke had the same degree of positive association in both groups. Respiratory infections in childhood and low socioeconomic class were significantly and homogeneously associated with both groups, whereas occupational exposure was significantly associated only with stage 0. All the GOLD stages showed a significantly higher percentage of healthcare resource users than healthy subjects (p",
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T1 - An international survey of chronic obstructive pulmonary disease in young adults according to GOLD stages

AU - De Marco, R.

AU - Accordini, S.

AU - Cerveri, I.

AU - Corsico, A.

AU - Sunyer, J.

AU - Neukirch, F.

AU - Künzli, N.

AU - Leynaert, B.

AU - Janson, C.

AU - Gislason, T.

AU - Vermeire, P.

AU - Svanes, C.

AU - Anto, J. M.

AU - Burney, P.

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N2 - Background: The recently published GOLD guidelines provide a new system for staging chronic obstructive pulmonary disease (COPD) from mild (stage I) to very severe (stage IV) and introduce a stage 0 (chronic cough and phlegm without airflow obstruction) that includes subjects "at risk" of developing the disease. Methods: In order to assess the prevalence of GOLD stages of COPD in high income countries and to evaluate their association with the known risk factors for airflow obstruction, data from the European Community Respiratory Health Survey on more than 18 000 young adults (20-44 years) were analysed. Results: The overall prevalence was 11.8% (95% CI 11.3 to 12.3) for stage 0, 2.5% (95% CI 2.2 to 2.7) for stage I, and 1.1% (95% CI 1.0 to 1.3) for stages II-III. Moderate to heavy smoking (≥ 5 pack years) was significantly associated with both stage 0 (relative risk ratio (RRR) = 4.15; 95% CI 3.55 to 4.84) and stages I+ (RRR = 4.09; 95% CI 3.17 to 5.26), while subjects with stages I+ COPD had a higher likelihood of giving up smoking (RRR = 1.39; 95% CI 1.04 to 1.86) than those with GOLD stage 0 (RRR = 1.05; 95% CI 0.86 to 1.27). Environmental tobacco smoke had the same degree of positive association in both groups. Respiratory infections in childhood and low socioeconomic class were significantly and homogeneously associated with both groups, whereas occupational exposure was significantly associated only with stage 0. All the GOLD stages showed a significantly higher percentage of healthcare resource users than healthy subjects (p

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