Abstract
The aim of this study was to evaluate the efficacy and safety of rivastigmine as add-on treatment to specific cognitive rehabilitation for unilateral spatial neglect (USN). Twenty patients were randomly assigned either to rehabilitation treatment only (No-RIV) or to rivastigmine (3 mg twice a day, for 8 weeks) add-on treatment (RIV+,). USN and functional status were evaluated by means of specific and validated instruments at baseline, at discharge and at one-month follow up. Compared with the untreated patients, the RIV+ subjects, at discharge, recorded significantly better discharge scores and higher effectiveness on two of the scales. However, subsequent further improvement of the No-RIV patients meant that at follow up there was no significant difference between the two groups. No other statistically significant difference was found. Rivastigmine as add-on treatment to specific cognitive training for USN may improve and accelerate recovery on some specific impairment tests as compared with cognitive training alone.
Original language | English |
---|---|
Pages (from-to) | 195-200 |
Number of pages | 6 |
Journal | Functional Neurology |
Volume | 25 |
Issue number | 4 |
Publication status | Published - Oct 2010 |
Keywords
- Neglect
- Rehabilitation
- Rivastigmine
- Stroke
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)