An unusual association of cerebral meningioma, parathyroid adenoma and thyroid papillary carcinoma

Chiara Caliumi, Dario Cotesta, Luigi Petramala, Monica Iorio, Maurizio Salvati, Sebastiano Filetti, Giorgio De Toma, Emilio D'Erasmo, Claudio Letizia

Research output: Contribution to journalArticlepeer-review


The case of a 50-year-old woman with cerebral meningioma and concomitant parathyroid adenoma and papillary thyroid carcinoma is presented. She complained of neurological symptoms characterized by right hemiparesis and dysarthria. Cerebral CT and MRI scans revealed a left voluminous frontal parasagittal lesion with the characteristics of a meningioma. Routine laboratory analysis revealed altered values of calcium-phosphorus metabolism. Intravenous infusion of saline solution at 0.9% of NaCl resulted in a reduction of serum ionized calcium. A left craniotomy was performed and a fibroblastic meningioma of 5 cm in diameter was removed. Even though the patient's clinical condition was good, a calcium-phosphorus metabolism test confirmed high plasma levels of ionized calcium and parathyroid hormone. Thyroid and parathyroid ultrasonography revealed multinodular goiter and a parathyroid lesion confirmed by 99mTc-TCO4/99mTc-MIBI scintigraphy. A left superior parathyroidectomy and total thyroidectomy were performed. Histological examination revealed a parathyroid adenoma and a small papillary carcinoma of 0.4 cm in the right thyroid lobe. As far as we know, this patient is the third case of meningioma associated with parathyroid adenoma and papillary thyroid carcinoma described in the literature.

Original languageEnglish
Pages (from-to)178-180
Number of pages3
Issue number2
Publication statusPublished - Mar 2006


  • Cerebral meningioma
  • Papillary thyroid carcinoma
  • Parathyroid adenoma

ASJC Scopus subject areas

  • Cancer Research


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