An unusual WPW syndrome: What is the preexcitation variant?

Hussam Ali, Antonio Sorgente, Guido De Ambroggi, Riccardo Cappato

Research output: Contribution to journalArticle


A 15-year-old female with WPW syndrome and normal heart underwent an electrophysiology study for paroxysmal palpitations and syncope. Intravenous adenosine produced an unexpected response of QRS changes and advanced AV block. During isoproteronol infusion, short-lasting and poorly tolerated wide QRS tachycardia was inducible, but pacing maneuvers were not feasible during tachycardia to determine its definitive mechanism. However, various electrophysiologic phenomena including adenosine response, junctional beats pattern, and multisite atrial pacing were helpful to overcome the diagnosis challenges. Finally, careful evaluation of tachycardia features and the comprehensive electrophysiology study were crucial to establish presence of unusual preexcitation variants, and thus to guide successful catheter ablation of the arrhythmic substrate.

Original languageEnglish
Pages (from-to)220-223
Number of pages4
JournalIndian Pacing and Electrophysiology Journal
Issue number4
Publication statusPublished - Jul 1 2015


  • Catheter ablation
  • Mahaim
  • Preexcitation variant
  • WPW syndrome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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