An update of laparoscopy in cervical cancer staging: Is it a useful procedure?

Pierluigi Benedetti Panici, Giorgia Perniola, Federica Tomao, Margherita Fischetti, Delia Savone, Violante Di Donato, Roberto Angioli, Ludovico Muzii

Research output: Contribution to journalArticle

Abstract

Objective: It was the aim of this study to report on the role of laparoscopic staging in a large series of locally advanced cervical cancer (LACC) patients and its impact on prognosis. Methods: Consecutive patients with LACC were considered for surgical staging: gynecological examination, cystoscopy and laparoscopy with peritoneal biopsies and peritoneal fluid cytology. Results: Between February 2000 and September 2010, a total of 167 women were evaluated. In 5 patients, laparoscopy could not be performed. One hundred and sixty-two patients had correct laparoscopic staging: 49 International Federation of Gynecology and Obstetrics (FIGO) stage IB-IIA (>4 cm), 67 IIB, 39 III, and 7 IVA. Abdominal spread was found in 33 cases (20%). There was a minor laparoscopy complication rate of 1%. We found a significant difference in the distribution of peritoneal spread for tumor grade and FIGO stage (p = 0.01 and p <0.0001, respectively), whereas no statistically significant difference for the histological type was found [p = not significant (NS)]. The median follow-up was 80 months (range 4-144). The median overall survival was 65 months. The patients without abdominal spread did not benefit from a significantly longer survival (median overall survival of 59 vs. 70 months; p = NS). Conclusions: Laparoscopic staging in cervical cancer is a safe and feasible technique but it does not modify the prognosis of LACC patients.

Original languageEnglish
Pages (from-to)160-165
Number of pages6
JournalOncology
Volume85
Issue number3
DOIs
Publication statusPublished - Oct 2013

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Keywords

  • Cervical cancer
  • Laparoscopic staging
  • Peritoneal spread

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Benedetti Panici, P., Perniola, G., Tomao, F., Fischetti, M., Savone, D., Di Donato, V., Angioli, R., & Muzii, L. (2013). An update of laparoscopy in cervical cancer staging: Is it a useful procedure? Oncology, 85(3), 160-165. https://doi.org/10.1159/000351995