TY - JOUR
T1 - Anabolic deficiencies in men with systolic heart failure
T2 - Do co-morbidities and therapies really contribute significantly?
AU - Kalicińska, Elzbieta
AU - Wojtas, Katarzyna
AU - Majda, Jacek
AU - Doehner, Wolfram
AU - Haehling, Stephan Von
AU - Banasiak, Waldemar
AU - Ponikowska, Beata
AU - Borodulin-Nadzieja, Ludmila
AU - Anker, Stefan D.
AU - Ponikowski, Piotr
AU - Jankowska, Ewa A.
PY - 2013/9
Y1 - 2013/9
N2 - Background: Deficiencies of anabolic hormones are common in men with heart failure (HF). It remains unclear whether the deranged metabolism of these hormones is the pathophysiological element of HF itself or is the consequence of co-morbidities or/and treatment in HF. Methods: We examined 382 men with systolic HF. Serum hormones (i.e. total testosterone [TT], DHEAS, IGF-1) were assessed using immunoassays, serum free testosterone (eFT)-using the Vermeulen equation. Results: Prevalence of TT and eFT deficiencies was similar in men with HF aged
AB - Background: Deficiencies of anabolic hormones are common in men with heart failure (HF). It remains unclear whether the deranged metabolism of these hormones is the pathophysiological element of HF itself or is the consequence of co-morbidities or/and treatment in HF. Methods: We examined 382 men with systolic HF. Serum hormones (i.e. total testosterone [TT], DHEAS, IGF-1) were assessed using immunoassays, serum free testosterone (eFT)-using the Vermeulen equation. Results: Prevalence of TT and eFT deficiencies was similar in men with HF aged
KW - Anabolic deficiency
KW - Dehydroepiandrosterone sulphate
KW - Heart failure
KW - Insulin-like growth factor 1
KW - Male ageing
KW - Testosterone
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U2 - 10.3109/13685538.2013.807427
DO - 10.3109/13685538.2013.807427
M3 - Article
C2 - 23803163
AN - SCOPUS:84883563275
VL - 16
SP - 123
EP - 131
JO - Aging Male
JF - Aging Male
SN - 1368-5538
IS - 3
ER -