Squilibrio anabolico/catabolico nello scompenso cardiaco cronico

Translated title of the contribution: Anabolic/catabolic imbalance in chronic heart failure

Antonio Cittadini, Eduardo Bossone, Alberto Maria Marra, Michele Arcopinto, Emanuele Bobbio, Salvatore Longobardi, Carmine Cevara, Sara Di Michele, Luigi Saccà

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A metabolic imbalance between anabolic drive and catabolic forces is commonly observed in chronic heart failure (CHF) patients, with the latter prevailing over anabolic hormones. Moreover, anabolic deficiencies are independent markers of poor prognosis. This finding represents a solid background for the implementation of therapeutic trials based on replacement therapy. The somatotropic axis (GH/IGF-1) is the most powerful anabolic axis of the body and its decline is related with a poor outcome and a worse clinical status. Growth hormone (GH) administration may enter the therapeutic arena as adjunctive treatment in patients affected by CHF and GH/IGF-1 deficiency. The T.O.S.CA. project aims at investigating the relationship between CHF and hormonal deficiency.

Original languageItalian
Pages (from-to)53-56
Number of pages4
JournalMonaldi Archives for Chest Disease - Cardiac Series
Volume74
Issue number2
Publication statusPublished - Jun 2010

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Heart Failure
Growth Hormone
Insulin-Like Growth Factor I
Therapeutics
Hormones

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine

Cite this

Cittadini, A., Bossone, E., Marra, A. M., Arcopinto, M., Bobbio, E., Longobardi, S., ... Saccà, L. (2010). Squilibrio anabolico/catabolico nello scompenso cardiaco cronico. Monaldi Archives for Chest Disease - Cardiac Series, 74(2), 53-56.

Squilibrio anabolico/catabolico nello scompenso cardiaco cronico. / Cittadini, Antonio; Bossone, Eduardo; Marra, Alberto Maria; Arcopinto, Michele; Bobbio, Emanuele; Longobardi, Salvatore; Cevara, Carmine; Di Michele, Sara; Saccà, Luigi.

In: Monaldi Archives for Chest Disease - Cardiac Series, Vol. 74, No. 2, 06.2010, p. 53-56.

Research output: Contribution to journalArticle

Cittadini, A, Bossone, E, Marra, AM, Arcopinto, M, Bobbio, E, Longobardi, S, Cevara, C, Di Michele, S & Saccà, L 2010, 'Squilibrio anabolico/catabolico nello scompenso cardiaco cronico', Monaldi Archives for Chest Disease - Cardiac Series, vol. 74, no. 2, pp. 53-56.
Cittadini A, Bossone E, Marra AM, Arcopinto M, Bobbio E, Longobardi S et al. Squilibrio anabolico/catabolico nello scompenso cardiaco cronico. Monaldi Archives for Chest Disease - Cardiac Series. 2010 Jun;74(2):53-56.
Cittadini, Antonio ; Bossone, Eduardo ; Marra, Alberto Maria ; Arcopinto, Michele ; Bobbio, Emanuele ; Longobardi, Salvatore ; Cevara, Carmine ; Di Michele, Sara ; Saccà, Luigi. / Squilibrio anabolico/catabolico nello scompenso cardiaco cronico. In: Monaldi Archives for Chest Disease - Cardiac Series. 2010 ; Vol. 74, No. 2. pp. 53-56.
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