Anaemia management in patients with inflammatory bowel disease: Routine practice across nine European countries

Jürgen Stein, Palle Bager, Ragnar Befrits, Christoph Gasche, Maja Gudehus, Eric Lerebours, Fernando Magro, Fermin Mearin, Daniell Mitchell, Bas Oldenburg, Silvio Danese

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND AND OBJECTIVES: Anaemia and iron deficiency (ID) are common complications in inflammatory bowel disease (IBD). In patients undergoing iron therapy, intravenous iron supplementation is recommended in preference to oral therapy. This study evaluated routine practice in the management of IBD-associated anaemia and ID to verify implementation of international treatment guidelines. MATERIALS AND METHODS: Gastroenterologists from nine European countries (n=344) were surveyed about their last five IBD patients treated for anaemia (n=1404). Collected information included tests performed at anaemia diagnosis, haemoglobin (Hb) levels and iron status parameters, the anaemia treatment given and, if applicable, the iron administration route. RESULTS: Selection of diagnostic tests and treatment for IBD-associated anaemia varied considerably across Europe. Anaemia and iron status were mainly assessed by Hb (88%) and serum ferritin (75%). Transferrin saturation was only tested in 25% of patients. At diagnosis of anaemia, 56% presented with at least moderate anaemia (Hb

Original languageEnglish
Pages (from-to)1456-1463
Number of pages8
JournalEuropean Journal of Gastroenterology and Hepatology
Volume25
Issue number12
DOIs
Publication statusPublished - Dec 2013

Keywords

  • intravenous iron
  • iron deficiency
  • iron replacement therapy
  • iron-deficiency anaemia

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

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