Anaerobic metabolism in hypertensive patients during exercise stress test

Giuseppe Olivo, Franceso Pestelli, Vincenzo Guarnaccia, Gian Franco Gensini, Pier Luigi Malfanti, Gian Gastone Neri Serneri

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

An impaired maximal vasodilating capacity has been reported in hypertensives. This study aimed to assess whether mild hypertensives depend on anaerobic metabolism more than do normal subjects during the exercise stress test. The oxygen uptake (Vo2) and carbon dioxide output (Vco2) were measured at the anaerobic threshold (AT) and at peak exercise (Vo2p and Vco2p) during the cardiopulmonary exercise test by breath-by-breath expiratory gas analysis in 21 mild hypertensives and 19 age-matched normotensives. AT was reached earlier in hypertensives than in normotensives, but with similar Vo2 uptake, Vco2 output, and Vco2/Vo2 ratio. At peak exercise, however, hypertensives showed lower Vo2p than controls (29 ± 5 υ 33 ± 5 mL Vo2/kg/min, (P 2p (36 ± 6 υ 39 ± 6 mL Vco2/kg/min, P =.19). As a result, the slope of carbon dioxide output increase versus oxygen uptake after anaerobic threshold was steeper in hypertensives than in controls (P 2 in hypertensives as compared with controls seems to reflect a greater involvement of the anaerobic metabolism to supplement energy output. Am J Hypertens 1994:7:469-473.

Original languageEnglish
Pages (from-to)469-473
Number of pages5
JournalAmerican Journal of Hypertension
Volume7
Issue number5
DOIs
Publication statusPublished - 1994

Fingerprint

Anaerobiosis
Anaerobic Threshold
Exercise Test
Carbon Dioxide
Exercise
Oxygen
Gases

Keywords

  • Exercise stress test
  • Hypertension
  • Oxygen consumption
  • Pulmonary ventilation

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Olivo, G., Pestelli, F., Guarnaccia, V., Gensini, G. F., Malfanti, P. L., & Serneri, G. G. N. (1994). Anaerobic metabolism in hypertensive patients during exercise stress test. American Journal of Hypertension, 7(5), 469-473. https://doi.org/10.1093/ajh/7.5.469

Anaerobic metabolism in hypertensive patients during exercise stress test. / Olivo, Giuseppe; Pestelli, Franceso; Guarnaccia, Vincenzo; Gensini, Gian Franco; Malfanti, Pier Luigi; Serneri, Gian Gastone Neri.

In: American Journal of Hypertension, Vol. 7, No. 5, 1994, p. 469-473.

Research output: Contribution to journalArticle

Olivo, G, Pestelli, F, Guarnaccia, V, Gensini, GF, Malfanti, PL & Serneri, GGN 1994, 'Anaerobic metabolism in hypertensive patients during exercise stress test', American Journal of Hypertension, vol. 7, no. 5, pp. 469-473. https://doi.org/10.1093/ajh/7.5.469
Olivo G, Pestelli F, Guarnaccia V, Gensini GF, Malfanti PL, Serneri GGN. Anaerobic metabolism in hypertensive patients during exercise stress test. American Journal of Hypertension. 1994;7(5):469-473. https://doi.org/10.1093/ajh/7.5.469
Olivo, Giuseppe ; Pestelli, Franceso ; Guarnaccia, Vincenzo ; Gensini, Gian Franco ; Malfanti, Pier Luigi ; Serneri, Gian Gastone Neri. / Anaerobic metabolism in hypertensive patients during exercise stress test. In: American Journal of Hypertension. 1994 ; Vol. 7, No. 5. pp. 469-473.
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